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Merck
모든 사진(4)

Key Documents

A6419

Sigma-Aldrich

Adenosine 5′-triphosphate disodium salt hydrate

microbial, BioReagent, suitable for cell culture, ≥99% (HPLC)

동의어(들):

ATP disodium salt

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About This Item

실험식(Hill 표기법):
C10H14N5Na2O13P3 · xH2O
CAS Number:
Molecular Weight:
551.14 (anhydrous basis)
MDL number:
UNSPSC 코드:
12352207
eCl@ss:
32160414
PubChem Substance ID:
NACRES:
NA.75

생물학적 소스

microbial

Quality Level

제품 라인

BioReagent

분석

≥99% (HPLC)

형태

powder

기술

cell culture | mammalian: suitable

solubility

H2O: 50 mg/mL

저장 온도

−20°C

SMILES string

O.[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O

InChI

1S/C10H16N5O13P3.2Na.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1

InChI key

NTBQNWBHIXNPRU-MSQVLRTGSA-L

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

Adenosine 5′-triphosphate (ATP) is essential for biological processes including neurotransmission, signal transduction, muscle contraction and cardiac function. ATP is the major energy potential for living systems. They are released from cells under stress and play a key role in immune response. ATP release from injured neurons and consequent breakdown leads to generation of adenosine. ATP may serve as a therapeutic option in anaesthesia and intensive care medicine for the management of pain. Elevated ATP levels are indicative of cell damage and inflammation.

애플리케이션

Adenosine 5′-triphosphate disodium salt hydrate has been used:
  • as a component of transfection mix for the transformation of CRISPR/Cas9 plasmid in parasites
  • in inflammasome activation assays in bone marrow derived macrophages
  • for the stimulation of macrophages
  • in nucleotide synthesis

생화학적/생리학적 작용

P2 purinergic agonist; increases activity of Ca2+-activated K+ channels; substrate for ATP-dependent enzyme systems

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Faceshields, Gloves, type N95 (US)


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Potential value of adenosine 5?-triphosphate (ATP) and adenosine in anaesthesia and intensive care medicine
Skrabanja ATP, et al.
British Journal of Anaesthesia, 94(5), 556-562 (2005)
Effect of interleukin-31 on septic shock through regulating inflammasomes and interleukin-1beta
Gu X, et al.
Experimental and Therapeutic Medicine, 16(1), 171-177 (2018)
Deuterated nucleotides as chemical probes of RNA structure: a detailed protocol for the enzymatic synthesis of a complete set of nucleotides specifically deuterated at ribose carbons
Tullius T, et al.
ScienceOpen Research (2018)
Adenosine and its receptors as therapeutic targets: an overview
Sachdeva S and Gupta M
Saudi Pharmaceutical Journal : SPJ : The Official Publication of the Saudi Pharmaceutical Society, 21(3), 245-253 (2013)
Pharmacology of adenosine receptors and their signaling role in immunity and inflammation
Pharmacology & Therapeutics, 21(3), 245-253 (2014)

프로토콜

Separation of Adenosine 5′-triphosphate disodium salt hydrate, BioXtra, ≥99% (HPLC), from microbial; Adenosine 5′-diphosphate sodium salt, bacterial, ≥95% (HPLC); 2′-Deoxyadenosine 5′-monophosphate, Sigma Grade, 98-100%

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