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Merck
모든 사진(2)

주요 문서

94141

Supelco

4-Chloro-α-cyanocinnamic acid

matrix substance for MALDI-MS, ≥95.0% (HPLC)

동의어(들):

3-(4-Chlorophenyl)-2-cyano-2-propenoic acid, 3-(4-Chlorophenyl)-2-cyanoacrylic acid, p-Chloro-α-cyanocinnamic acid, p-Chlorobenzylidenecyanoacetic acid, ClCCA, NSC 2479

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About This Item

실험식(Hill 표기법):
C10H6ClNO2
CAS Number:
Molecular Weight:
207.61
Beilstein:
2616773
MDL number:
UNSPSC 코드:
12000000
PubChem Substance ID:
NACRES:
NA.21

Grade

matrix substance for MALDI-MS

Quality Level

분석

≥95.0% (HPLC)

양식

crystals

분석물 기능적 분류

drugs of abuse, ionic liquids

분석물 화학적 분류

chlorinated lipids, lipids, peptides, phospholipids, phosphopeptides

기술

MALDI-MS: suitable

solubility

methanol: 100 mg/10 mL, clear, colorless to light yellow

SMILES string

OC(=O)\C(=C\c1ccc(Cl)cc1)C#N

InChI

1S/C10H6ClNO2/c11-9-3-1-7(2-4-9)5-8(6-12)10(13)14/h1-5H,(H,13,14)/b8-5+

InChI key

MXCRRKYUQNHWLJ-VMPITWQZSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

애플리케이션

  • suitable as MALDI-Matrix material
  • suitable for collision-induced dissociation MS/MS (CID-MS/MS)

관련 제품

제품 번호
설명
가격

픽토그램

Skull and crossbones

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Maurice H J Selman et al.
Proteomics, 12(9), 1337-1348 (2012-05-17)
For MALDI analysis of glycans and glycopeptides, the choice of matrix is crucial in minimizing desialylation by mass spectrometric in-source and metastable decay. Here, we evaluated the potential of 4-chloro-α-cyanocinnamic acid (Cl-CCA) for MALDI-TOF-MS analysis of labile sialylated tryptic N-glycopeptides
Maja Pučić Baković et al.
Journal of proteome research, 12(2), 821-831 (2013-01-10)
Age and sex dependence of subclass specific immunoglobulin G (IgG) Fc N-glycosylation was evaluated for 1709 individuals from two isolated human populations. IgGs were obtained from plasma by affinity purification using 96-well protein G monolithic plates and digested with trypsin.
Joerg Flemmig et al.
Chemistry and physics of lipids, 161(1), 44-50 (2009-07-07)
The binding of the heme enzyme myeloperoxidase to phosphatidylserine epitopes on the surface of non-vital polymorphonuclear leukocytes and other cells at inflammatory sites favours modifications of this phospholipid by myeloperoxidase products. As detected by MALDI-TOF mass spectrometry hypochlorous acid and
Florian Baum et al.
Journal of agricultural and food chemistry, 61(38), 9110-9117 (2013-09-03)
Multiphosphorylated peptides endogenously present in milk exert anticariogenic activity due to their calcium binding capacity. This study performed comprehensive analysis of multiphosphorylated peptides in raw milk using matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS). Since phosphopeptides are often negatively
John D Leszyk
Journal of biomolecular techniques : JBT, 21(2), 81-91 (2010-07-02)
MALDI-TOF continues to be an important tool for many proteomic studies. Recently, a new rationally designed matrix 4-chloro-alpha-cyanocinnamic acid was introduced, which is reported to have superior performance as compared with the "gold standard" alpha-cyano-4-hydroxycinnamic acid (CHCA). In this study

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