ABE438

Anti-Apobec1 Antibody

from rabbit, purified by affinity chromatography

• 동의어(들): C->U-editing enzyme APOBEC-1, Apolipoprotein B mRNA-editing enzyme 1, HEPR
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 정제법: affinity chromatography
• 종 반응성: human, rat
• 기술: immunohistochemistry: suitable (paraffin); western blot: suitable
• NCBI 수납 번호: NP_001635
• UniProt 수납 번호: P41238
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... APOBEC1(339)

설명

일반 설명

Apolipoprotein B mRNA-editing enzyme 1 (Apobec1) is also known as C->U-editing enzyme APOBEC-1, and HEPR. Apobec1 is a member of the cytidine and deoxycytidylate deaminase family that is exclusively expressed in the small intestine. Apobec1 is a catalytic component of the apolipoprotein B mRNA editing enzyme complex which is responsible for postranscriptional mRNA editing. Apobec1 is also thought to be involved in the epigenetic regulation of gene expression by participating in DNA demethylation.

특이성

Other homologies: Mouse (79% sequence homology).

면역원

KLH-conjugated linear peptide corresponding to human Apobec1.

애플리케이션

Detect Apobec1 using this rabbit polyclonal antibody, Anti-Apobec1 Antibody validated for use in western blotting & IHC (Paraffin).

Immunohistochemistry Analysis: A 1:500-2,000 dilution from a representative lot detected Apobec1 in rat small intestine and human colon tissue.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Transcription Factors

품질

Evaluated by Western Blotting in human spleen tissue lysate.

Western Blotting Analysis: 0.1 µg/mL of this antibody detected Apobec1 in 10 µg of human spleen tissue lysate.

표적 설명

~28 kDa observed

물리적 형태

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

분석 메모

Control
Human spleen tissue lysate

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable