8.51061

2-Chlorotrityl chloride

Novabiochem^®

• 동의어(들): 2-Chlorotrityl chloride
• 실험식(Hill 표기법): C₁₉H₁₄Cl₂
• CAS Number: 42074-68-0
• Molecular Weight: 313.22
• MDL number: MFCD00040399
• UNSPSC 코드: 12352107
• EC 인덱스 번호: 255-647-3
• NACRES: NA.22

속성

• Quality Level: 200
• 제품 라인: Novabiochem^®
• 분석: ≥95.0% (HPLC)
• 양식: powder
• 제조업체/상표: Novabiochem^®
• mp: 133.0-137.0 °C
• 응용 분야: peptide synthesis
• 저장 온도: 2-30°C
• InChI: 1S/C19H14Cl2/c20-18-14-8-7-13-17(18)19(21,15-9-3-1-4-10-15)16-11-5-2-6-12-16/h1-14H
• InChI key: JFLSOKIMYBSASW-UHFFFAOYSA-N

설명

일반 설명

Hyperacid-labile ester protecting group ^[1]. Introduced under extremely mild conditions by reacting together the acid, trityl chloride and DIPEA in DCM. Ideal for the protection of the C-terminal carboxylic acid group of C-terminal protected peptide fragments, monoprotection of diacids and as a general carboxylic acid protecting group in organic synthesis.


Associated Protocols and Technical Articles
Guide to Selection of Orthogonally-Protected Building Blocks for Fmoc SPPS

Literature references

^[1] P. Athanassopoulos, et al. (1995) Tetrahedron Lett., 36, 5645.

결합

Replaces: 01-63-0045

분석 메모

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Melting range (lower value): ≥ 133 °C
Melting range (upper value): ≤ 137 °C
Assay (HPLC, area%): ≥ 95.0 % (a/a)

법적 정보

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS05,GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H290 - H315 - H319 - H335
• 예방조치 성명서: P234 - P261 - P264 - P271 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 8A - Combustible, corrosive hazardous materials
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable