8.18737

Chlorotrimethylsilane

for synthesis

• 동의어(들): Chlorotrimethylsilane, Trimethylchlorosilane, Trimethylsilyl chloride, TMCS
• Linear Formula: (CH₃)₃SiCl
• CAS Number: 75-77-4
• Molecular Weight: 108.64
• MDL number: MFCD00000502
• UNSPSC 코드: 12352103
• EC 인덱스 번호: 200-900-5
• NACRES: NA.22

속성

• vapor pressure: 250 hPa ( 20 °C)
• Quality Level: 200
• 분석: ≥99.0% (GC)
• 양식: liquid
• autoignition temp.: 420 °C
• 효능: 4868 mg/kg LD₅₀, oral (Rat); 1530 mg/kg LD₅₀, skin (Rabbit)
• expl. lim.: 1.5-46 % (v/v)
• bp: 57 °C/1013 hPa
• mp: -58 °C
• 전이 온도: flash point -20 °C
• density: 0.86 g/cm³ at 20 °C
• 저장 온도: 2-30°C
• InChI: 1S/C3H9ClSi/c1-5(2,3)4/h1-3H3
• InChI key: IJOOHPMOJXWVHK-UHFFFAOYSA-N

설명

애플리케이션

• Synthesis of bis ferrocene derivatives: Development of new ferrocenyl multi-functional silyl ether compounds using chlorotrimethylsilane, highlighting advances in organosilicon chemistry (R Teimuri-Mofrad et al., 2016).
• Pharmacologically active derivatives: Use of chlorotrimethylsilane as a catalyst in the synthesis of pharmacologically active bis (indolyl) and tris (indolyl) derivatives, demonstrating its efficiency in electrophilic substitution reactions (NG Singh et al., 2014).
• Silicone resin synthesis: Exploration of the hydrolysis-condensation reaction of tetraethoxysilane and chlorotrimethylsilane to create silicone resins, showing the material′s enhanced properties for industrial applications (CFJ Kuo et al., 2014).
• Deoxygenation of unsymmetrical dicarbonyl compounds: Innovative use of chlorotrimethylsilane and sodium iodide for the selective reduction of 1,2-diketones, showcasing a novel method in organic synthesis (LZ Yuan et al., 2016).
• Enhanced activity and durability of catalysts: Investigation into Fe3+ and chlorotrimethylsilane modified NaY catalysts for the acetalization of glycerol to solketal, improving catalytic performance in chemical processes (Y Li et al., 2023).

분석 메모

Assay (GC, area%): ≥ 99.0 % (a/a)
Density (d 20 °C/ 4 °C): 0.858 - 0.861
Identity (IR): passes test

안전성 정보

• 픽토그램: GHS02,GHS05,GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H225 - H301 + H331 - H312 - H314
• 예방조치 성명서: P210 - P233 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1A
• 보충제 위험성: EUH014
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point (°F): -18.4 °F - closed cup
• Flash Point (°C): -28 °C - closed cup