52619

Hexamethyldisilazane

for GC derivatization, LiChropur^™, ≥99.0% (GC)

• 동의어(들): HMDS
• Linear Formula: (CH₃)₃SiNHSi(CH₃)₃
• CAS Number: 999-97-3
• Molecular Weight: 161.39
• Beilstein: 635752
• EC Number: 213-668-5
• MDL number: MFCD00008259
• UNSPSC 코드: 12000000
• PubChem Substance ID: 329757861
• NACRES: NA.22

속성

• Grade: for GC derivatization
• Quality Level: 100
• 분석: ≥99.0% (GC)
• 형태: liquid
• 품질: LiChropur^™
• 반응 적합성: reagent type: derivatization reagent; reaction type: Silylations
• 기술: gas chromatography (GC): suitable
• refractive index: n20/D 1.407 (lit.); n20/D 1.408
• bp: 125 °C (lit.)
• SMILES string: C[Si](C)(C)N[Si](C)(C)C
• InChI: 1S/C6H19NSi2/c1-8(2,3)7-9(4,5)6/h7H,1-6H3
• InChI key: FFUAGWLWBBFQJT-UHFFFAOYSA-N

설명

일반 설명

Hexamethyldisilazane (HMDS) is a commercially available, silylating agent, which is used as an alternative for the preparation of silyl ethers from hydroxyl compounds.

애플리케이션

Learn more in the Product Information

Hexamethyldisilazane is suitable for the derivatization of alcohols, U-aminobutyric acid, pesticidal carbamates and urea, 3,4-Dihydroxyphenylglycol, 4-hydroxycoumarins, hydroxyfatty acids, n-hydroxy-2-fluorenylacetamide, kerb cycle acid, malonaldehyde, monoglycerides, phenylpyruvic acid, shikimic acid, unsaturated fatty acid esters (or methyl esters), and related compounds.

It may be used as a derivatizing reagent for the analysis of bioamines and their acidic metabolites, phenol, hydroquinone and catechol in urine samples, mixtures of free fatty acids and metal soaps in paint samples using gas chromatography/mass spectrometry (GC/MS).

Suitable for the derivatization of alcohols, Υ-aminobutyric acid, pesticidal carbamates and urea, 3,4-Dihydroxyphenylglycol, 4-hydroxycoumarins, hydroxyfatty acids, n-hydroxy-2-fluorenylacetamide, kerb cycle acid, malonaldehyde, monoglycerides, phenylpyruvic acid, shikimic acid, unsaturated fatty acid esters (or methyl esters), and related compounds.

특징 및 장점

• HMDS is inexpensive and has a relatively low boiling point (124-127 °C).        
• It can be used without solvent but its silylating power can be increased by various (mostly acidic) catalysts.        
• The only reaction byproduct, ammonia, can leave the reaction mixture as the reaction goes to completion.

기타 정보

Important silylating agent

Reagent for 2-hydroxypyrimidine, polytrimethylsilyloxy, trimethylsilyl and trimethylsilyl oximes.

법적 정보

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS02,GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H225,H302 + H332,H311,H412
• 예방조치 성명서: P210 - P273 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Flam. Liq. 2
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point (°F): 52.5 °F - closed cup
• Flash Point (°C): 11.4 °C - closed cup
• 개인 보호 장비: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter