5.09455

Etomoxir

≥98% (HPLC), liquid, CPT-1 inhibitor, Calbiochem^®

• 동의어(들): InSolution Etomoxir, R(+)-2-[6-(4-Chlorophenoxy)hexyl]-oxirane-2-carboxylic acid sodium salt hydrate
• 실험식(Hill 표기법): C₁₅H₁₈ClO₄ · Na
• CAS Number: 828934-41-4
• Molecular Weight: 320.74
• MDL number: MFCD07787411
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• 제품명: Etomoxir, InSolution, ≥98%, 50 mM aqueous solution, shown to inhibit carnitine palmitoyltransferase (CPT)-1 and DGAT activity
• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: liquid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; avoid repeated freeze/thaw cycles; protect from light
• 저장 온도: −70°C
• SMILES string: [Na+].Clc1ccc(cc1)OCCCCCC[C@]2(OC2)C(=O)[O-]
• InChI: 1S/C15H19ClO4.Na/c16-12-5-7-13(8-6-12)19-10-4-2-1-3-9-15(11-20-15)14(17)18;/h5-8H,1-4,9-11H2,(H,17,18);/q;+1/p-1/t15-;/m1./s1
• InChI key: RPACBEVZENYWOL-XFULWGLBSA-M

설명

일반 설명

A cell-permeable, irreversible, and stereospecific compound that is shown to inhibit carnitine palmitoyltransferase (CPT)-1 and DGAT activity in the mitochondria of rat heart H9c2 myoblastic cells at a concentration of 1-80 µM and 40 µM, respectively.

생화학적/생리학적 작용

Primary Target
CPT1

포장

Packaged under inert gas

경고

Toxicity: Standard Handling (A)

물리적 형태

A 50 mM (2 mg/118 µL) solution of Etomoxir (Cat. No. 236020) in H₂O.

재구성

Following initial thaw, aliquot and freeze (-70°C). Aliquots are stable for up to 6 months at -70°C.

기타 정보

Xu, F.Y., et al. 2003. J. Lipid Res.44, 415.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable