376817-M

Hexokinase II Inhibitor II, 3-BP

The Hexokinase II Inhibitor II, 3-BP, also referenced under CAS 1113-59-3, controls the biological activity of Hexokinase II. This small molecule/inhibitor is primarily used for Cell Structure applications.

• 동의어(들): Hexokinase II Inhibitor II, 3-BP, 3-BrPA, Bromopyruvate, Bromopyruvatic Acid, 3-Bromo-2-oxopropionic acid
• 실험식(Hill 표기법): C₃H₃BrO₃
• CAS Number: 1113-59-3
• Molecular Weight: 166.96
• MDL number: MFCD00002587
• UNSPSC 코드: 12352200
• EC 인덱스 번호: 214-206-5

속성

• Quality Level: 100
• 분석: ≥97% (titration)
• 양식: crystalline solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze
• 색상: white
• solubility: DMSO: 100 mg/mL; distilled water: 100 mg/mL
• 저장 온도: 2-8°C
• InChI: 1S/C3H3BrO3/c4-1-2(5)3(6)7/h1H2,(H,6,7)
• InChI key: PRRZDZJYSJLDBS-UHFFFAOYSA-N

설명

일반 설명

A cell-permeable pyruvic acid derivative that acts as an inhibitor against hexokinase II-mediated glycolysis and effectively suppress tumor survival both in cultures in vitro and in mice and rats in vivo.

경고

Toxicity: Corrosive (L)

재구성

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

기타 정보

Bujis, M., et al. 2009. Invest. New Drugs27, 120.
Chen, Z., et al. 2009. Biochim. Biophys. Acta.1787, 553.
Hulleman, E., et al. 2009. Blood.113, 2014;
Mathupala, S.P., et al. 2009. Semin. Cancer Biol.19, 17.
Pereira da Silva, A.P., et al. 2009. Biochem. J.417, 717.
Yun, J., et al. 2009. Science.325, 1555.
Zhang, X., et al. 2009. Anticancer Res.29, 1443.
Kim, J.S., et al. 2008. J. Bioenerg. Biomembr.40, 607.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS05
• 신호어: Danger
• 유해 및 위험 성명서: H314
• 예방조치 성명서: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Hazard Classifications: Eye Dam. 1 - Skin Corr. 1B
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable