추천 제품
생물학적 소스
mouse
Quality Level
결합
ALEXA FLUOR™ 488
항체 형태
purified immunoglobulin
항체 생산 유형
primary antibodies
클론
4.47, monoclonal
종 반응성
human, rat, mouse
제조업체/상표
Upstate®
기술
flow cytometry: suitable
immunocytochemistry: suitable
western blot: suitable
동형
IgG1
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
타겟 번역 후 변형
unmodified
유전자 정보
human ... PTK2(5747)
특이성
p125FAK, does not cross react with Pyk-2
면역원
GST fusion protein corresponding to residues 1-423 of human FAK (focal adhesion kinase)
애플리케이션
Detect FAK using this Anti-FAK Antibody, clone 4.47, Alexa Fluor 488 conjugate validated for use in FC, WB & IC.
Research Category
Signaling
Signaling
Research Sub Category
Cytoskeletal Signaling
Cytoskeletal Signaling
품질
Routinely evaluated by immunostaining of 3T3 cells.
표적 설명
125kDa
물리적 형태
Protein G Purified
저장 및 안정성
1 year at 4°C from date of shipment
법적 정보
ALEXA FLUOR is a trademark of Life Technologies
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
면책조항
Alexa Fluor™ is a registered trademark of Molecular Probes, Inc.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Frontiers in bioscience : a journal and virtual library, 8, d982-d996 (2003-04-18)
Focal adhesion kinase (FAK) was first described in 1992 as a novel nonreceptor protein-tyrosine kinase localized prominently within focal adhesions, suggesting a signaling role in regulating cell behavior resulting from integrin interaction with the extracellular matrix. Subsequent studies over the
Focal adhesion kinase: in command and control of cell motility.
Nature Reviews in Molecular and Cell Biology, 6, 56-68 (2005)
Control of motile and invasive cell phenotypes by focal adhesion kinase.
Biochimica et Biophysica Acta, 1692, 77-102 (2004)
JCI insight, 2(11) (2017-06-02)
Microglia play a critical role in the development and homeostasis of the CNS. While mobilization of microglia is critical for a number of pathologies, understanding of the mechanisms of their migration in vivo is limited and often based on similarities
FAK and paxillin: regulators of N-cadherin adhesion and inhibitors of cell migration?
The Journal of cell biology, 166, 157-159 (2004)
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