추천 제품
생물학적 소스
mouse
Quality Level
항체 형태
purified immunoglobulin
항체 생산 유형
primary antibodies
클론
2A7, monoclonal
종 반응성
human, mouse, rat, avian
제조업체/상표
Upstate®
기술
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
동형
IgG1
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
타겟 번역 후 변형
unmodified
유전자 정보
human ... PTK2(5747)
특이성
Recognizes FAK.
면역원
Mixture of affinity-purified tyrosine phosphoproteins from chick embryo fibroblasts expressing p125FAK.
애플리케이션
Anti-FAK Antibody, clone 2A7 detects level of FAK & has been published & validated for use in IC & IP.
Not recommended in Western Blot
Research Category
Signaling
Signaling
Research Sub Category
Cytoskeletal Signaling
Cytoskeletal Signaling
품질
routinely evaluated by immunoprecipitation of FAK from a mouse 3T3/A31 RIPA cell lysate, subsequently immunobloted with Anti-FAK (Catalog #06-543)
표적 설명
125 kDa
결합
Replaces: 04-591
물리적 형태
Format: Purified
Protein G Purified
Protein G Purified immunoglobulin in Protein G Purified immunoglobulin in Purified immunoglobulin in 10mM PBS, pH 7.4 containing no preservatives.
저장 및 안정성
Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
분석 메모
Control
Expressed in most tissue, 3T3/A31 cell lysate
Expressed in most tissue, 3T3/A31 cell lysate
법적 정보
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Tyrosine phosphorylation of paxillin and focal adhesion kinase during insulin-like growth factor-I-stimulated lamellipodial advance.
Leventhal, P S, et al.
The Journal of Biological Chemistry, 272, 5214-5218 (1997)
Ambivalent role of pFAK-Y397 in serous ovarian cancer--a study of the OVCAD consortium.
Aust, S; Auer, K; Bachmayr-Heyda, A; Denkert, C; Sehouli, J; Braicu, I; Mahner et al.
Molecular Cancer null
F Burgaya et al.
The Journal of biological chemistry, 272(45), 28720-28725 (1997-11-14)
pp125 focal adhesion kinase (FAK), a cytoplasmic tyrosine kinase transducing signals initiated by integrin engagement and G protein-coupled receptors, is highly expressed in brain. FAK from brain had a higher molecular weight and an increased autophosphorylation activity, than from other
Variations of proline-rich kinase Pyk2 expression correlate with prostate cancer progression.
R Stanzione, A Picascia, P Chieffi, C Imbimbo, A Palmieri, V Mirone, S Staibano, R Franco et al.
Laboratory Investigation; a Journal of Technical Methods and Pathology null
P Derkinderen et al.
Science (New York, N.Y.), 273(5282), 1719-1722 (1996-09-20)
Anandamide is an endogenous ligand for central cannabinoid receptors and is released after neuronal depolarization. Anandamide increased protein tyrosine phosphorylation in rat hippocampal slices and neurons in culture. The action of anandamide resulted from the inhibition of adenylyl cyclase and
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