추천 제품
생물학적 소스
mouse
Quality Level
항체 형태
purified immunoglobulin
항체 생산 유형
primary antibodies
클론
5E12.2, monoclonal
종 반응성
human, mouse
기술
western blot: suitable
동형
IgG1κ
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
타겟 번역 후 변형
unmodified
유전자 정보
human ... IZUMO1R(390243)
일반 설명
Folates are necessary and critical components in the synthesis of proteins and nucleic acids, and have putative roles in the development of both the spinal canal and brain in the early stages of pregnancy (Yamaguchi, 2007). Folate receptor 4 (Folr4) is a recently discovered cell surface receptor for folic acid on T regulatory cells (Tregs). Studies have shown that Folr4 has an integral role in the maintenance of Treg cell function (Arase, 2009). Expression of Folr4 in Tregs is notably high, making it an opportune marker for the study of Treg cells. When studied in conjunction with CD4 and CD25, Folr4 also provides researchers with a marker to distinguish between Tregs and other T cells (Chai, 2008). Tregs are of interest in therapeutic, drug research due to their ability to actively suppress immune responses.
특이성
This antibody recognizes Folate receptor 4 (Folr4).
면역원
Epitope: Unknown
KLH-conjugated linear peptide corresponding to human Folate receptor 4 (Folr4).
애플리케이션
Anti-Folr4 (Folate receptor 4) Antibody, clone 5E12.2 detects level of Folr4 (Folate receptor 4) & has been published & validated for use in WB.
Research Category
Inflammation & Immunology
Inflammation & Immunology
Research Sub Category
Inflammation & Autoimmune Mechanisms
Inflammation & Autoimmune Mechanisms
Western Blot (SNAP ID) Analysis: 1 µg/mL of this antibody detected Folate receptor 4 (Folr4) in 10 µg of human thymus tissue lysate.
품질
Evaluated by Western Blot in human thymus tissue lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected Folate receptor 4 (Folr4) in 10 µg of human thymus tissue lysate.
A previous lot was shown to detect Folate Receptor 4 in mouse thymus tissue lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected Folate receptor 4 (Folr4) in 10 µg of human thymus tissue lysate.
A previous lot was shown to detect Folate Receptor 4 in mouse thymus tissue lysate.
표적 설명
~26 kDa
물리적 형태
Format: Purified
Protein G Purified
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.
저장 및 안정성
Stable for 1 year at 2-8°C from date of receipt.
분석 메모
Control
Human thymus tissue lysate
Human thymus tissue lysate
기타 정보
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
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