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Merck
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V-902

Supelco

Vardenafil dihydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

실험식(Hill 표기법):
C23H32N6O4S·2HCl
CAS Number:
224785-90-4
Molecular Weight:
561.52
EC Number:
200-659-6
MDL number:
MFCD04972607
UNSPSC 코드:
41116107
PubChem Substance ID:
329830239
NACRES:
NA.24

Grade

certified reference material

양식

liquid

특징

Snap-N-Spike®/Snap-N-Shoot®

포장

ampule of 1 mL

제조업체/상표

Cerilliant®

농도

1.0 mg/mL in methanol (as free base)

기술

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

응용 분야

pharmaceutical (small molecule)

형식

single component solution

저장 온도

−20°C

SMILES string

O=C(C1=C(C)N=C(CCC)N1N2)N=C2C3=CC(S(=O)(N4CCN(CC)CC4)=O)=CC=C3OCC.Cl.Cl

InChI

1S/C23H32N6O4S.2ClH/c1-5-8-20-24-16(4)21-23(30)25-22(26-29(20)21)18-15-17(9-10-19(18)33-7-3)34(31,32)28-13-11-27(6-2)12-14-28;;/h9-10,15H,5-8,11-14H2,1-4H3,(H,25,26,30);2*1H

InChI key

NOIHTGOGFDFCBN-UHFFFAOYSA-N

유전자 정보

human ... PDE5A(8654)

일반 설명

Vardenafil, a phosphodiesterase inhibitor, is used to treat erectile dysfunction. This Snap-N-Spike® reference solution is applicable for use in urine drug testing, clinical toxicology or forensic analysis by LC-MS/MS or GC/MS. Vardenafil is sold under the trade names Levitra® and Staxyn®.

법적 정보

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Levitra is a registered trademark of Bayer Aktiengesellschaft
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Staxyn is a registered trademark of Bayer Aktiengesellschaft

픽토그램

FlameSkull and crossbonesHealth hazard
GHS02,GHS06,GHS08

신호어

Danger

유해 및 위험 성명서

H225,H301 + H311 + H331,H370

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

표적 기관

Eyes,Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point (°F)

49.5 °F - closed cup

Flash Point (°C)

9.7 °C - closed cup

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시험 성적서(COA)

Lot/Batch Number

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이미 열람한 고객

Slide 1 of 2

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Sildenafil Citrate Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1807

Sildenafil Citrate

Sildenafil citrate European Pharmacopoeia (EP) Reference Standard

Y0001578

Sildenafil citrate

Christoph Zenzmaier et al.
Endocrinology, 153(11), 5546-5555 (2012-09-06)
Phosphodiesterase type 5 (PDE5) inhibitors have been demonstrated to improve lower urinary tract symptoms secondary to benign prostatic hyperplasia (BPH). Because BPH is primarily driven by fibroblast-to-myofibroblast trans-differentiation, this study aimed to evaluate the potential of the PDE5 inhibitor vardenafil
S I Gamidov et al.
Urologiia (Moscow, Russia : 1999), (3)(3), 102-104 (2013-08-31)
Due to high efficiency, prompt action and low incidence of side effects, phosphodiesterase type 5 inhibitors are the drugs of first choice in the treatment of erectile dysfunction (ED). One of the most widely used drugs in this group currently
Valter Javaroni et al.
Urology, 80(4), 858-864 (2012-08-28)
To evaluate whether the response to on-demand vardenafil could be improved by its daily usage in hypertensive men with erectile dysfunction (ED) who previously did not answer to on-demand regime. Our main efficacy criterion was per patient percentage of positive
B Henriet et al.
Revue medicale de Bruxelles, 33(3), 146-152 (2012-08-16)
Recent societal evolutions have enabled more and more men to talk about erectile dysfunction (ED). There is a strong association between ED and cardiovascular disease and ED should now be considered as an early clinical evidence of vascular disorder. Inhibitors
Daniel J Mans et al.
Journal of pharmaceutical and biomedical analysis, 75, 153-157 (2012-12-25)
Ion mobility spectrometry was used as a rapid screening tool for the detection of acetildenafils, sildenafils and avanafil within adulterated herbal supplement matrices. Acetildenafils show a tendency for partial fragmentation during the desorption/ionization process affording two peaks in the ion
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