T-072

Tadalafil solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

• 실험식(Hill 표기법): C₂₂H₁₉N₃O₄
• CAS Number: 171596-29-5
• Molecular Weight: 389.40
• EC Number: 200-835-2
• MDL number: MFCD07771966
• UNSPSC 코드: 41116107
• PubChem Substance ID: 329826616
• NACRES: NA.24

속성

• Grade: certified reference material
• 형태: liquid
• 특징: Snap-N-Spike^®/Snap-N-Shoot^®
• 포장: ampule of 1 mL
• 제조업체/상표: Cerilliant^®
• 농도: 1.0 mg/mL in acetonitrile
• 기술: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 응용 분야: pharmaceutical (small molecule)
• 형식: single component solution
• 저장 온도: −20°C
• SMILES string: O=C1N(C)CC(N2[C@H](C3=CC(OCO4)=C4C=C3)C5=C(C(C=CC=C6)=C6N5)C[C@@]21[H])=O
• InChI: 1S/C22H19N3O4/c1-24-10-19(26)25-16(22(24)27)9-14-13-4-2-3-5-15(13)23-20(14)21(25)12-6-7-17-18(8-12)29-11-28-17/h2-8,16,21,23H,9-11H2,1H3/t16-,21-/m1/s1
• InChI key: WOXKDUGGOYFFRN-IIBYNOLFSA-N
• 유전자 정보: human ... PDE5A(8654)

설명

일반 설명

Tadalafil is an erectile-dysfunction drug marketed under the trade name Cialis^®. This Certified Spiking Solution^® is suitable for use in numerous testing applications such as clinical toxicology, forensic analysis, urine drug testing, or calibrator preparation.

애플리케이션

• Universal Quantitation of PDE5 Inhibitors: A study highlights the use of high-performance liquid chromatography with charged aerosol detection to universally quantitate undeclared phosphodiesterase-5 inhibitors, including tadalafil, in herbal dietary supplements. This method ensures the integrity of dietary supplements and protects consumers from potential health risks (Poplawska et al., 2013).


• Drug Screening with 3D-Printed Electrochemical Cells: Research developed a multi-sensor compatible 3D-printed electrochemical cell for voltammetric drug screening, applicable to tadalafil and other drugs. This innovative approach enhances drug analysis efficiency and accuracy, facilitating rapid screening in pharmaceutical research (Ferreira et al., 2021).


• Solid Dispersions for Enhanced Solubility: A study on the physical stability of solid dispersions of tadalafil in PVP-VA investigates the thermodynamic solubility of the drug, critical for improving bioavailability in pharmaceutical formulations. This research contributes to the development of more effective and reliable drug delivery systems (Wlodarski et al., 2015).

법적 정보

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Cialis is a registered trademark of Eli Lilly and Co.

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS02,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H225,H302 + H312 + H332,H319
• 예방조치 성명서: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point (°F): 35.6 °F - closed cup
• Flash Point (°C): 2 °C - closed cup