N-007

Naltrexone solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• 실험식(Hill 표기법): C₂₀H₂₃NO₄
• CAS Number: 16590-41-3
• Molecular Weight: 341.40
• MDL number: MFCD00242996
• UNSPSC 코드: 41116107
• PubChem Substance ID: 329818395
• NACRES: NA.24

속성

• Grade: certified reference material
• 형태: liquid
• 특징: Snap-N-Spike^®/Snap-N-Shoot^®
• 포장: ampule of 1 mL
• 제조업체/상표: Cerilliant^®
• 농도: 1.0 mg/mL in methanol
• 기술: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 응용 분야: forensics and toxicology
• 형식: single component solution
• 배송 상태: wet ice
• 저장 온도: 2-8°C
• SMILES string: Oc1ccc2C[C@H]3N(CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O)CC6CC6
• InChI: 1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1
• InChI key: DQCKKXVULJGBQN-XFWGSAIBSA-N
• 유전자 정보: human ... OPRD1(4985) , OPRK1(4986) , OPRM1(4988)

설명

일반 설명

Naltrexone is an opiate sold under the trade names Revia, Depade and Vivitrol^® and is prescribed primarily for the management of alcohol or opiate dependence. This analytical reference standard is applicable for use in LC/MS or GC/MS applications such as pharmaceutical research, forensic analysis, clinical toxicology, pain prescription monitoring or urine drug testing.

애플리케이션

• Naltrexone research solution: Research utilizes naltrexone in thermosensitive gels to enhance microneedle-assisted transdermal delivery, showcasing its potential for non-invasive therapeutic applications and improving drug bioavailability (Polymers (Basel), 2021; doi: 10.3390/polym13060933).


• Opioid receptor antagonist: A study discusses the historical context of opioid use disorder trials, with naltrexone featured as a pivotal medication in optimizing treatment strategies. This research underscores its importance in addiction studies and the development of effective treatment modalities (Addict Sci Clin Pract, 2021; doi: 10.1186/s13722-021-00223-z).


• Naltrexone in vitro study: The compound is utilized in a model of ocular neuropathic pain, highlighting its utility in pain management research and its potential role in developing new therapeutic strategies for chronic pain conditions (Transl Vis Sci Technol, 2019; doi: 10.1167/tvst.8.2.6).


• Naltrexone pharmacological research: Research on Mg²⁺ influx modulation in cardiac myocytes provides insights into ionic exchanges in heart tissues, demonstrating naltrexone′s broader applications in physiological and pharmacological studies (J Physiol Sci, 2019; doi: 10.1007/s12576-018-0625-5).


• Naltrexone biochemistry application: A study explores mechanical stimulation for reducing ethanol self-administration in rats, indicating naltrexone′s utility in experimental models of addiction and its potential application in behavioral sciences (Evid Based Complement Alternat Med, 2017; doi: 10.1155/2017/6578621).

추천 제품

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

법적 정보

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Vivitrol is a registered trademark of Alkermes, Inc.

안전성 정보

• 픽토그램: GHS02,GHS06,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H225,H301 + H311 + H331,H370
• 예방조치 성명서: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 표적 기관: Eyes,Central nervous system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point (°F): 49.5 °F - closed cup
• Flash Point (°C): 9.7 °C - closed cup