M-021

(±)-Methadone-D3 solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• 동의어(들): DL-Methadone-d₃ solution, DL-6-Dimethylamino-4,4-diphenyl-3-heptanone-1,1,1-d₃ solution, DL-Methadone-(heptyl-1,1,1-d₃) solution
• 실험식(Hill 표기법): C₂₁D₃H₂₄NO
• CAS Number: 60263-63-0
• Molecular Weight: 312.46
• EC Number: 200-659-6
• MDL number: MFCD00673285
• UNSPSC 코드: 41116107
• PubChem Substance ID: 329817743
• NACRES: NA.24

속성

• Grade: certified reference material
• Quality Level: 300
• 형태: liquid
• 특징: Snap-N-Spike^®/Snap-N-Shoot^®
• 포장: ampule of 1 mL
• 제조업체/상표: Cerilliant^®
• drug control: Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
• 농도: 1.0 mg/mL in methanol
• 기술: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 응용 분야: forensics and toxicology
• 형식: single component solution
• 질량 이동: M+3
• 저장 온도: 2-8°C
• SMILES string: [2H]C([2H])([2H])CC(=O)C(CC(C)N(C)C)(c1ccccc1)c2ccccc2
• InChI: 1S/C21H27NO/c1-5-20(23)21(16-17(2)22(3)4,18-12-8-6-9-13-18)19-14-10-7-11-15-19/h6-15,17H,5,16H2,1-4H3/i1D3
• InChI key: USSIQXCVUWKGNF-FIBGUPNXSA-N

설명

일반 설명

A stable-labeled internal standard applicable for use in isotope dilution methods or quantitation of methadone levels by GC/MS or LC/MS in forensic analysis, urine drug testing, pain prescription monitoring or clinical toxicology applications. Methadone is a synthetic opioid used medically as an analgesic and as a maintenance anti-addictive for use in patients with opioid dependency. The drug is sold under several trade names such as Symoron, Dolophine^®, Amidone, Methadose^®, Physeptone, or Heptadon.

애플리케이션

• Opioid pharmacokinetics research: (±)-Methadone-D3 solution is utilized in opioid pharmacokinetics research to track and analyze the metabolism of methadone, providing insights into its pharmacological properties and interaction dynamics (Beck et al., 2010).


• MethaDonemetabolism study: As a deuterated methaDonesolution, it is critical for detailed studies on drug metabolism, aiding in the understanding of methadone′s biotransformation and its implications for therapeutic efficacy and safety (Anggård et al., 1979).


• Mass spectrometry internal standard: Methadone-D3 serves as an internal standard in mass spectrometry, enhancing the precision of quantitative analyses in forensic and clinical toxicology (Johansen and Jensen, 2004).


• Analytical research: Employed in analytical research, Methadone-D3 solution facilitates the development of advanced analytical methods for the detection and quantification of opioids in various biological matrices (Lucas et al., 2000).


• Drug metabolism research: This solution is key in drug metabolism research, helping to identify the metabolic pathways and excretion profiles of methadone, which is crucial for developing effective dosing regimens and understanding drug interactions (Kintz et al., 1998).

법적 정보

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Dolophine is a registered trademark of Roxane Laboratories, Inc.

Methadose is a registered trademark of Mallinckrodt Inc.

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS02,GHS06,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H225,H301 + H311 + H331,H370
• 예방조치 성명서: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 표적 기관: Eyes
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point (°F): 49.5 °F - closed cup
• Flash Point (°C): 9.7 °C - closed cup