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900130E

Avanti

13(S)HODE

Avanti Research™ - A Croda Brand (900130E), ethanol solution

동의어(들):

13S-Hydroxy-9Z,11E-octadecanoic acid

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모든 사진(1)

About This Item

실험식(Hill 표기법):
C18H32O3
CAS Number:
29623-28-7
Molecular Weight:
296.44
MDL number:
MFCD00065833
UNSPSC 코드:
12352211
NACRES:
NA.25

분석

99% (TLC)

양식

ethanol solution

포장

pkg of 1 × 1 mg (900130E-1mg)
pkg of 1 × 500 μg (900130E-500ug)

제조업체/상표

Avanti Research™ - A Croda Brand (900130E)

농도

1 mg/mL (900130E-1MG)
500 μg/mL (900130E-500UG)

지질 유형

neutral glycerides
neutral lipids

배송 상태

dry ice

저장 온도

−70°C

SMILES string

O[C@@H](CCCCC)\C=C\C=C/CCCCCCCC(=O)O

InChI

1S/C18H32O3/c1-2-3-11-14-17(19)15-12-9-7-5-4-6-8-10-13-16-18(20)21/h7,9,12,15,17,19H,2-6,8,10-11,13-14,16H2,1H3,(H,20,21)/b9-7-,15-12+/t17-/m0/s1

InChI key

HNICUWMFWZBIFP-IRQZEAMPSA-N

일반 설명

13-S-hydroxyoctadecadienoic acid (13(S)HODE) is a metabolite of 15-lipoxygenase (15-LOX). It is an endogenous ligand of peroxisome proliferator-activated receptorγ (PPARγ).

생화학적/생리학적 작용

13-S-hydroxyoctadecadienoic acid (13(S)HODE) inhibits cell proliferation and induces apoptosis in many human cancers. It also enhances the activity of nuclear factor κ light chain enhancer of activated B cells (NF-κB) in keratinocytes.

포장

2ml Amber Glass Sealed Ampule

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

픽토그램

FlameExclamation mark
GHS02,GHS07

신호어

Danger

유해 및 위험 성명서

H225,H319

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point (°F)

55.4 °F

Flash Point (°C)

13 °C

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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Huiling Yuan et al.
Thorax, 65(4), 321-326 (2010-04-15)
15-S-Hydroxyeicosatetraenoic acid (15(S)-HETE) and 13-S-hydroxyoctadecadienoic acid (13(S)-HODE), both of which are metabolites of 15-lipoxygenases (15-LOXs), are endogenous ligands for peroxisome proliferator-activated receptor gamma (PPARgamma). The activation of PPARgamma inhibits cell growth and induces apoptosis in some cancers. The role of
Eisaku Ogawa et al.
The Journal of investigative dermatology, 131(3), 604-612 (2010-11-12)
Fatty acid-binding proteins (FABPs) are postulated to serve as lipid shuttles that solubilize hydrophobic fatty acids and deliver them to appropriate intracellular sites. Epidermal FABP (E-FABP/FABP5) is predominantly expressed in keratinocytes and is overexpressed in the actively proliferating tissue characteristic

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