콘텐츠로 건너뛰기
Merck
모든 사진(1)

Key Documents

860676P

Avanti

C16 Ceramide-d7 (d18:1-d7/16:0)

Avanti Research - A Croda Brand 860676P, powder

동의어(들):

N-palmitoyl-D-erythro-sphingosine (d7)

로그인조직 및 계약 가격 보기


About This Item

실험식(Hill 표기법):
C34H60D7NO3
CAS Number:
Molecular Weight:
544.94
UNSPSC 코드:
12352100
NACRES:
NA.12

형태

powder

포장

pkg of 1 × 1 mg (860676P-1mg)

제조업체/상표

Avanti Research - A Croda Brand 860676P

배송 상태

dry ice

저장 온도

−20°C

SMILES string

OC[C@]([H])(NC(CCCCCCCCCCCCCCC)=O)[C@@](O)([H])/C=C/CCCCCCCCCCC(C(C([2H])([2H])[2H])([2H])[2H])([2H])[2H]

일반 설명

C16 Ceramide (d18:1/16:0) is a synthetic ceramide containing sphingosine with palmitic acid. It is synthesized from ceramide synthase 6 (CerS6). C16 Ceramide-d7 (d18:1-d7/16:0) is a deuterated derivative of ceramide d18:1/16:0.

애플리케이션

C16 Ceramide-d7 (d18:1-d7/16:0), has been used as a standard to measure the amount of C16 ceramide in skeletal muscle by liquid chromatography–mass spectrometry (LC-MS).

생화학적/생리학적 작용

C16 Ceramide plays a vital role in apoptotic signaling. Examining the levels of the ceramides (Cer) d18:1/16:0, Cer d18:1/18:0, Cer d18:1/24:0, and Cer d18:1/24:1 and ratios in human plasma facilitates the prognosis of fatal outcome of coronary artery disease. A newly described and validated liquid chromatography-tandem mass spectrometry methodology uses C16 Ceramide (d18:1/16:0) in a stable isotope form for their clinical-scaled measurement.

포장

5 mL Amber Glass Screw Cap Vial (860676P-1mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

Flash Point (°F)

No data available

Flash Point (°C)

No data available


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

이미 열람한 고객

Dimple Kauhanen et al.
Analytical and bioanalytical chemistry, 408(13), 3475-3483 (2016-02-29)
Monitoring the levels of the ceramides (Cer) d18:1/16:0, Cer d18:1/18:0, Cer d18:1/24:0, and Cer d18:1/24:1 and ratios thereof in human plasma empowers the prediction of fatal outcome of coronary artery disease (CAD). We describe a validated liquid chromatography-tandem mass spectrometry
Anna Zalewska et al.
Biomolecules, 9(12) (2019-12-19)
This is the first study to investigate the relationship between ceramides, the mitochondrial respiratory system, oxidative stress, inflammation, and apoptosis in the submandibular gland mitochondria of mice with insulin resistance (IR). The experiment was conducted on 20 male C57BL/6 mice
Hady Razak Hady et al.
Journal of clinical medicine, 8(12) (2019-12-18)
The liver plays a central role in the glucose and lipid metabolism. Studies performed on animal models have shown an important role of lipid accumulation in the induction of insulin resistance. We sought to explain whether in obese humans, the
Paul T Reidy et al.
The Journal of physiology, 596(21), 5217-5236 (2018-09-09)
Insulin sensitivity (as determined by a hyperinsulinaemic-euglyceamic clamp) decreased 15% after reduced activity. Despite not fully returning to baseline physical activity levels, insulin sensitivity unexpectedly, rebounded above that recorded before 2 weeks of reduced physical activity by 14% after the recovery

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

고객지원팀으로 연락바랍니다.