추천 제품
분석
>99% (TLC)
양식
liquid
포장
pkg of 1 × 1 mL (810222C-250ug)
pkg of 1 × 1 mg (81022C-1MG)
제조업체/상표
Avanti Research™ - A Croda Brand 810222C
농도
0.25 mg/mL (810222C-250ug)
배송 상태
dry ice
저장 온도
−20°C
일반 설명
C6-NBD Glucosyl Ceramide is a fluorescent derivative of biologically active compound, glucosyl ceramide. Glucosyl ceramide belongs to the class of sphingolipids that are synthesized in the cis/medial-Golgi apparatus by the glycosylation of ceramide.
애플리케이션
C6-NBD Glucosyl Ceramide may be used as a substrate for glucocerebrosidase (GCase) activity assay in Drosophila melanogaster and mice.
생화학적/생리학적 작용
Glucosylceramide is the precursor of different glycosphingolipids including gangliosides and sulfatides. Glucosyl ceramide is also known to be responsible for axon growth of neural cells. The accumulation of glucosyl ceramide is associated with an inherited lysosomal storage disorder, Gaucher′s disease.
포장
5 mL Amber Glass Screw Cap Vial (81022C-1MG)
5 mL Clear Glass Sealed Ampule (810222C-250ug)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
표적 기관
Central nervous system
WGK
WGK 3
가장 최신 버전 중 하나를 선택하세요:
H Zhao et al.
Cellular and molecular life sciences : CMLS, 59(4), 694-707 (2002-05-23)
Gaucher disease is an autosomal recessive trait and the most common lysosomal storage disease. The pathogenesis evolves from the diminished activity of the lysosomal hydrolase, acid beta-glucosidase and the resultant accumulation of glucosylceramide within lysosomes. The pathogenic mechanisms are poorly
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