QBD10513

Azido-dPEG^®₁₂-acid

• 동의어(들): Polyethylene glycol, alpha-(2-azidoethyl)-omega-(2-carboxyethoxy)poly(oxy-1,2-ethanediyl)
• 실험식(Hill 표기법): C₂₇H₅₃N₃O₁₄
• CAS Number: 1167575-20-3
• Molecular Weight: 643.72
• MDL number: MFCD21363301
• UNSPSC 코드: 12352106
• PubChem Substance ID: 329823935
• NACRES: NA.22

속성

• 분석: >90%
• 형태: solid or viscous liquid
• 반응 적합성: reaction type: click chemistry; reagent type: cross-linking reagent; reaction type: click chemistry
• 폴리머 구조: shape: linear; functionality: heterobifunctional
• 배송 상태: ambient
• 저장 온도: −20°C
• SMILES string: OC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O

설명

특징 및 장점

The azido-dPEG^®₁₂ contains an azide function on one end of a single molecular weight dPEG^® spacer (46.4 Å) and a reactive group on the other end of the spacer. The dPEG^® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. The reactive acid functional group may be activated with 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) or N,N′-dicyclohexylcarbodiimide (DCC) for conjugation to an amine. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.

법적 정보

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable