추천 제품
Quality Level
분석
≥97.5% (sum of enantiomers, HPLC)
양식
powder
저장 온도
2-8°C
SMILES string
Nc1nc(O)c2nc(cnc2n1)[C@H](O)[C@H](O)CO
InChI
1S/C9H11N5O4/c10-9-13-7-5(8(18)14-9)12-3(1-11-7)6(17)4(16)2-15/h1,4,6,15-17H,2H2,(H3,10,11,13,14,18)/t4-,6+/m1/s1
InChI key
BMQYVXCPAOLZOK-XINAWCOVSA-N
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일반 설명
D-(+)-Neopterin is a pteridine derivative, naturally found in Dictyostelium discoideum. It is found in significant amounts in the urine of cancer patients.
애플리케이션
D-(+)-Neopterin has been used as a NADPH oxidase inhibitor while assessing the ability of NADPH oxidases in breast cancer cells to produce reactive oxygen species (ROS). [NADPH= nicotinamide adenine dinucleotide phosphate]
생화학적/생리학적 작용
Pterin cofactor; precursor of BH4 (tetrahydrobiopterin).
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
이미 열람한 고객
Dictyopterin, 6-(d-threo-1,2-dihydroxypropyl)-pterin, a new natural isomer of L-biopterin.
European Journal of Biochemistry, 187(3), 665-669 (1990)
Pteridine analysis in urine by capillary electrophoresis using laser-induced fluorescence detection.
Analytical Chemistry, 71(7), 1265-1269 (1999)
Ferroptosis is induced following siramesine and lapatinib treatment of breast cancer cells.
Cell Death & Disease, 7(7), e2307-e2307 (2016)
Mediators of inflammation, 2012, 476979-476979 (2012-09-13)
The serum levels of neopterin, a marker associated with cell-mediated immunity are elevated in chronic kidney disease (CKD). We evaluated serum neopterin levels and investigated its association with markers of inflammation in a cross-section of CKD subjects without known cardiovascular
Transplantation, 95(8), 1021-1029 (2013-04-18)
Plasmapheresis (PP) has been used in the treatment of various immunologic disorders, and its efficacy has mainly been attributed to the removal of humoral factors and autoantibodies. Besides these effects, PP may induce modifications of the cellular immunologic status, contributing
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