L040031

Cap A

• UNSPSC 코드: 12352200

속성

• 유형: for DNA synthesis
• Quality Level: 200
• 제품 라인: Proligo Reagents
• 농도: 97.0-119.0 g/L (acetic anhydride, titration)
• 색상: clear colorlessto brownish

설명

일반 설명

Cap A solution consists of acetic anhydrideanhydride, lutidine, and tetrahydrofuran (THF).

애플리케이션

Cap A solution is used after the phosphoramidite reaction/coupling step.

생화학적/생리학적 작용

Cap A solution aborts chains bearing unreacted 5′ hydroxyl groups due to failure of reaction with activated phosphoramidite (typically, 1 to 2% of growing oligonucleotide chains in each synthesis cycle). These unreacted 5′ hydroxyl groups are capped with an acetyl group and thus rendered unreactive for subsequent synthesis steps.

안전성 정보

• 픽토그램: GHS02,GHS06,GHS08,GHS05
• 신호어: Danger
• 유해 및 위험 성명서: H225,H302,H315,H318,H331,H335,H336,H351
• 예방조치 성명서: P210 - P280 - P301 + P312 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• 보충제 위험성: EUH019
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3