901573

Bromo-PEG₁-acid

≥95%

• 실험식(Hill 표기법): C₅H₉BrO₃
• CAS Number: 1393330-33-0
• Molecular Weight: 197.03
• MDL number: MFCD22574802
• UNSPSC 코드: 12352101

속성

• 분석: ≥95%
• 형태: powder, crystals or chunks
• 반응 적합성: reagent type: linker
• 작용기: bromo; carboxylic acid
• 저장 온도: −20°C
• SMILES string: BrCCOCCC(O)=O

설명

애플리케이션

Bromo-PEG₁-acid is a heterobifunctional, PEGylated crosslinker featuring a bromo group at one end and a carboxyl group at the other. The hydrophillic PEG linker facilitates solubility in biological applications. Bromo-PEG₁-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC^® molecules) for targeted protein degradation.

This is a crosslinker with a bromo group on one end and a carboxyl group on the other end. The compound contains a single PEG unit to help improve solubility.

법적 정보

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3