746118

Sodium difluoroheptylazidosulfinate

95%

• 동의어(들): Baran DAAS-Na Reagent, Sodium 1,1-difluoro-7-azido-heptylsulfinate, Sodium 7-azido-1,1-difluoroheptanesulfinate
• 실험식(Hill 표기법): C₇H₁₂F₂N₃NaO₂S
• CAS Number: 1450912-63-6
• Molecular Weight: 263.24
• UNSPSC 코드: 12352125
• PubChem Substance ID: 329765744
• NACRES: NA.22

속성

• Quality Level: 100
• 분석: 95%
• 형태: solid
• 반응 적합성: reaction type: C-C Bond Formation; reagent type: catalyst; reaction type: C-H Activation; reagent type: linker
• 작용기: azide; fluoro; sulfinic acid
• 저장 온도: 2-8°C
• SMILES string: [Na+].[O-]S(=O)C(F)(F)CCCCCCN=[N+]=[N-]
• InChI: 1S/C7H13F2N3O2S.Na/c8-7(9,15(13)14)5-3-1-2-4-6-11-12-10;/h1-6H2,(H,13,14);/q;+1/p-1
• InChI key: FFNHIEJQAMGBCZ-UHFFFAOYSA-M

설명

애플리케이션

Within heteroarene platforms, DAAS-Na allows for the direct introduction of a difluoroalkyl chain carrying an azide group, which is designed for the purpose of bioconjugation. Through a Huisgen cycloaddition (a "click" reaction), the azide moiety can then be reacted with a terminal alkyne that is bound to a functional molecule such as biomacromolecules. This effectively allows for a covalent linkage between a heteroarene and any target molecule, for example, between a heteroarene-containing drug and an antibody. This reagent was developed by the Baran Group and is one of several reagents for the direct alkylation of heterocycles.

Learn More at the Professor and Product Portal of Professor Phil S. Baran.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable