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Merck
모든 사진(1)

Key Documents

523429

Sigma-Aldrich

2,3-Dibromo-1,4-naphthoquinone

97%

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About This Item

실험식(Hill 표기법):
C10H4Br2O2
CAS Number:
Molecular Weight:
315.95
EC Number:
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

분석

97%

mp

218-222 °C (lit.)

작용기

bromo
ketone

SMILES string

BrC1=C(Br)C(=O)c2ccccc2C1=O

InChI

1S/C10H4Br2O2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H

InChI key

PSMABVOYZJWFBV-UHFFFAOYSA-N

관련 카테고리

일반 설명

2,3-Dibromo-1,4-naphthoquinone is a 2,3-disubstituted 1,4-naphthoquinone. It is a plumbagin derivative and an acaricide. It undergoes photochemical reaction with 2-methoxy-1-alkene to yield derivatives of 2-(2-alkanonyl)-1,4-naphthoquinone.

애플리케이션

2,3-Dibromo-1,4-naphthoquinone may be used in the synthesis of 3-[3-(2-carboxy-ethylsulfanyl)-1,4-dioxo-1,4-dihydro-naphthalen-2-ylsulfanyl]-propionic acid and NSC 95397 (a protein tyrosine phosphatase antagonist).

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


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시험 성적서(COA)

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문서 라이브러리 방문

A new method of ?-keto alkyl chain introduction into 1, 4-naphthoquinone.
Maruyama K, et al.
Chemistry Letters (Jpn), 13(3), 371-374 (1984)
Chi-Hoon Lee et al.
Journal of microbiology and biotechnology, 18(2), 314-321 (2008-03-01)
Acaricidal effects of materials derived from Diospyros kaki roots against Dermatophagoides farinae and D. pteronyssinus were assessed using impregnated fabric disk bioassay and compared with that of the commercial benzyl benzoate. The observed responses varied according to dosage and mite
A one-pot synthesis of 1, 4-naphthoquinone-2, 3-bis-sulfides catalysed by a commercial laccase.
Wellington KW, et al.
Green Chemistry, 14(9), 2567-2576 (2012)
Vincent P Peyregne et al.
Molecular cancer therapeutics, 4(4), 595-602 (2005-04-14)
Cdc25 phosphatases are important in cell cycle control and activate cyclin-dependent kinases (Cdk). Efforts are currently under way to synthesize specific small-molecule Cdc25 inhibitors that might have anticancer properties. NSC 95397, a protein tyrosine phosphatase antagonist from the National Cancer
Xiao-Fei Shang et al.
Scientific reports, 8(1), 1609-1609 (2018-01-27)
As important secondary plant metabolites, naphthoquinones exhibit a wide range of biological activities. However, their potential as sustainable alternatives to synthetic acaricides has not been studied. This study for the first time investigates the acaricidal activity of naphthoquinones against Psoroptes

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