38827
4,4′-Dimethoxytriphenylmethyl chloride
≥97.0% (HPLC)
동의어(들):
4,4′-Dimethoxytrityl chloride, Chloro-4,4′-dimethoxytriphenylmethane, DMT, DMT-Cl
로그인조직 및 계약 가격 보기
모든 사진(1)
About This Item
실험식(Hill 표기법):
C21H19ClO2
CAS Number:
Molecular Weight:
338.83
Beilstein:
2471942
EC Number:
MDL number:
UNSPSC 코드:
12352101
PubChem Substance ID:
NACRES:
NA.22
추천 제품
Quality Level
분석
≥97.0% (HPLC)
mp
123-125 °C
작용기
chloro
phenyl
SMILES string
COc1ccc(cc1)C(Cl)(c2ccccc2)c3ccc(OC)cc3
InChI
1S/C21H19ClO2/c1-23-19-12-8-17(9-13-19)21(22,16-6-4-3-5-7-16)18-10-14-20(24-2)15-11-18/h3-15H,1-2H3
InChI key
JBWYRBLDOOOJEU-UHFFFAOYSA-N
유전자 정보
human ... HTR2A(3356) , HTR2B(3357) , HTR2C(3358)
rat ... Htr1a(24473) , Htr2a(29595)
애플리케이션
4,4′-Dimethoxytriphenylmethyl chloride (DMTrCl) can be used as a protecting agent:
- For hydroxyl group of nucleosides/nucleotides as its O-(4,4′-dimethoxytrityl)derivative.
- For 10 sulfhydryl group of oligonucleotide analogs as its DMTr thioether.
기타 정보
Useful protecting-group reagent; Removal
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
8B - Non-combustible corrosive hazardous materials
WGK
WGK 3
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
이미 열람한 고객
M.P. Reddy et al.
Tetrahedron Letters, 28, 23-23 (1987)
V. Amarnath et al.
Chemical Reviews, 77, 183-183 (1977)
Selective protection and deprotection procedures for thiol and hydroxyl groups
Huang Z and Benner SA
Synlett, 1993(01), 83-84 (1993)
A novel entry to 2′-O-aminopropyl modified nucleosides amenable for further modifications
Haas J and Engels JW
Tetrahedron Letters, 48(50), 8891-8894 (2007)
2′-Deoxyimmunosine: stereoselective synthesis, base pairing and duplex stability of oligonucleotides containing 8-oxo-7-thiaguanine
Seela F and Ming X
Organic & Biomolecular Chemistry, 6(8), 1450-1461 (2008)
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