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Merck
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Key Documents

226351

Sigma-Aldrich

N-Hydroxymaleimide

97%, for peptide synthesis

동의어(들):

1-Hydroxypyrrole-2,5-dione

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About This Item

실험식(Hill 표기법):
C4H3NO3
CAS Number:
Molecular Weight:
113.07
Beilstein:
1524594
EC Number:
MDL number:
UNSPSC 코드:
12352005
PubChem Substance ID:
NACRES:
NA.22

product name

N-Hydroxymaleimide, 97%

Quality Level

분석

97%

형태

solid

반응 적합성

reaction type: Addition Reactions

mp

130-133 °C (dec.) (lit.)

응용 분야

peptide synthesis

작용기

imide
maleimide

SMILES string

ON1C(=O)C=CC1=O

InChI

1S/C4H3NO3/c6-3-1-2-4(7)5(3)8/h1-2,8H

InChI key

BUXKULRFRATXSI-UHFFFAOYSA-N

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일반 설명

N-Hydroxymaleimide (NHMI) is an organic compound that is widely used as an oxidizing agent in organic synthesis. It is frequently used to selectively oxidize thiols to disulfides and in the synthesis of α, β-unsaturated carbonyl compounds. It can also act as a Michael acceptor and is used in the synthesis of peptides and proteins.

애플리케이션

N-Hydroxymaleimide can be used as an oxidant to generate N-hydroxy anilines in situ, which serve as key intermediates in the selective coupling reaction of N-substituted anilines with hydroxylamine derivatives, for the efficient synthesis of aromatic oximes.

픽토그램

Corrosion

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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