추천 제품
분석
97%
형태
solid
mp
130-133 °C (lit.)
SMILES string
CN1C(=O)C(=O)c2ccccc12
InChI
1S/C9H7NO2/c1-10-7-5-3-2-4-6(7)8(11)9(10)12/h2-5H,1H3
InChI key
VCYBVWFTGAZHGH-UHFFFAOYSA-N
유전자 정보
human ... CASP3(836)
일반 설명
The interaction between 1-methylisatin and human adult haemoglobin was studied using the circular dichroism (CD) spectroscopic, anisotropy and FTIR investigations.
애플리케이션
- Reactant for stereoselective preparation of spirobicyclic and bis-spirotricyclic pyrazolidinones
- Reactant for regioselective preparation of spirocyclic oxindole-butenolides
- Reactant for synthesis of spiro-oxindoles
- Reactant for preparation of unsymmetrical oxindoles
- Reactant for stereoselective preparation of hydroxyloxindoles via Morita-Baylis-Hillman reaction
- Reactant for preparation of pyridinecarboxylic acid [(oxo)indolylidene)hydrazide derivatives (Schiff base hydrazides) as antibacterial agents
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 3 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
이미 열람한 고객
Jaime F Martínez Suárez et al.
The Journal of organic chemistry, 84(11), 6879-6885 (2019-05-16)
Isatin in a solution of dry N,N-dimethylformamide/NaClO4 is electroreduced in the presence of CH3I. N-methylisatin (NMI) is obtained in quantitative molar yield and high current efficiency by controlled potential electrolysis (CPE). NMI and N-methylisatoic anhydride are the reaction products when
L Sebastian et al.
Letters in applied microbiology, 55(3), 234-239 (2012-06-29)
To investigate the drug to drug interaction of N-methylisatin-β-thiosemicarbazone (MIBT) derivative (SCH16) with ribavirin, mycophenolic acid and pentoxifylline against Japanese encephalitis virus in vitro. Our earlier studies have reported significant antiviral activity of these compounds against Japanese encephalitis virus in
María C Rodríguez-Argüelles et al.
Journal of inorganic biochemistry, 101(1), 138-147 (2006-10-31)
Cobalt(II), nickel(II), copper(II) and zinc(II) complexes of 2-thiophenecarbonyl and isonicotinoyl hydrazones of 3-(N-methyl)isatin (HL(1) and HL(2), respectively) were synthesized and characterized, being the crystal structures of HL(1), HL(2) and [Ni(L(1))(2)].2CHCl(3) elucidated by X-ray diffraction techniques. The in vitro antimicrobial activity
M S Mirrlees et al.
Drug design and discovery, 11(3), 223-230 (1994-04-01)
Alkaline hydrolysis of the title isatin 4 in unbuffered solution obeys a rate law such that kobs varies; is directly proportional to [OH-]2 at pH 10 changes smoothly to kobs varies; is directly proportional to [OG-] by pH 13. As
Verena Schulz et al.
Organic letters, 9(9), 1745-1748 (2007-03-31)
[reaction: see text] The in situ preparation of a sulfonium ylide reagent achieved the highly diastereoselective epoxidation of isatins, so that a new and straightforward access to biologically significant spiro-epoxyoxindoles is provided. The first investigations of an asymmetric version are
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