129445
Indole-3-carboxaldehyde
97%
동의어(들):
β-Indolylaldehyde, 3-Formylindole, 3-Indolylformaldehyde, Indole-3-carbaldehyde, NSC 10118
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C9H7NO
CAS Number:
Molecular Weight:
145.16
Beilstein:
114117
EC Number:
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
NACRES:
NA.22
추천 제품
일반 설명
Indole-3-carboxaldehyde can undergo Schiff bases condensation to form multifunctional silica nano-vehicles and magnetic nanoparticles.
애플리케이션
Indole-3-carboxaldehyde was used to prepare analogs of the indole phytoalexin cyclobrassinin with NR1R2 group. It was also used as the starting material for the synthesis of higher order indoles including isoindolo[2,1-a]indoles, aplysinopsins, and 4-substituted-tetrahydrobenz[cd]indoles.
Reactant for preparation of:
- Analgesic agents
- Hypoglycemic agents
- Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
- Antibacterial and antifungal agents
- Antiamoebic and cytotoxic agents
- Inhibitors of the Dengue virus protease with antiviral activity in cell-culture
- Curcumin analogues as possible anti-proliferative & anti-inflammatory agents
- Inhibitors of Bcl-2 family proteins
- Inhibitors of the C-terminal domain of RNA Polymerase II as antitumor agents
- Inhibitors of TNF-α and IL-6 with anti-tubercular activity
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
이미 열람한 고객
Qiu-Yun Chen et al.
Colloids and surfaces. B, Biointerfaces, 114, 158-163 (2013-11-05)
Multifunctional silica nano-vehicles (SiO2@indol-IL) and magnetic nanoparticles (Fe3O4@indol-IL) were constructed through the Schiff bases condensation of indole-3-carboxaldehyde and 4-acetyl-N-allyl pyridinium chloride (ILs) with the amine groups of silica and magnetic nanoparticles. SiO2@indol-IL can inhibit the proliferation of HepG-2 cells in
Synthetic Communications, 23, 55-55 (1993)
Heterocycles, 38, 1479-1479 (1994)
Mariana Budovská et al.
Bioorganic & medicinal chemistry, 21(21), 6623-6633 (2013-09-10)
An effective synthesis of analogs of the indole phytoalexin cyclobrassinin with NR1R2 group instead of SCH3 was developed starting from indole-3-carboxaldehyde. The target compounds were prepared by spirocyclization of 1-Boc-thioureas with the formation of isolable spiroindoline intermediates, followed by the
Indian J. Chem. B, 33, 4-4 (1994)
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