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Merck
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Key Documents

108448

Sigma-Aldrich

Cyanoacetamide

99%

동의어(들):

2-Cyanoacetamide

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About This Item

Linear Formula:
NCCH2CONH2
CAS Number:
Molecular Weight:
84.08
Beilstein:
878221
EC Number:
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
NACRES:
NA.22

분석

99%

mp

119-121 °C (lit.)

solubility

cold water: soluble 1gm in 6.5ml

작용기

amide

SMILES string

NC(=O)CC#N

InChI

1S/C3H4N2O/c4-2-1-3(5)6/h1H2,(H2,5,6)

InChI key

DGJMPUGMZIKDRO-UHFFFAOYSA-N

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일반 설명

Cyanoacetamide is the starting reagent for vitamin B6 synthesis. It reacts with reducing carbohydrates in borate buffer to give intense fluorescence andis useful for the automated analysis of carbohydrates as borate complexes.

Cyanoacetamide is a highly reactive compound used as a reaction intermediate in condensation and substitution reactions.

애플리케이션

Cyanoacetamide was used in spectrofluorimetric method for the determination of some antihistaminic H1 receptor antagonist drugs such as ebastine, cetirizine dihydrochloride and fexofenadine hydrochloride. It may be used in fluorometric determination of 3,4-dihydroxyphenylalanine. It was used as post column fluorigenic derivatizing agent for the bio-analysis and pharmacokinetics of chitosan ester in rabbit serum.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

419.0 °F - closed cup

Flash Point (°C)

215 °C - closed cup

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


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Fluorimetric determination of reducing carbohydrates with 2-cyanoacetamide and application to automated analysis of carbohydrates as borate complexes.
Honda S, et al.
Analytical Chemistry, 52(7), 1079-1082 (1980)
Fluorometric determination of 3, 4-dihydroxyphenylalanine with 2-cyanoacetamide.
Liu Y, et al.
Journal of Fluorescence, 13(2), 123-128 (2003)
Spectrofluorimetric Determination Of Some H1 Receptor Antagonist Drugs In Pharmaceutical Formulations And Biological Fluids.
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International Journal of Pharmaceutical Sciences and Research, 2(8), 2056-2072 (2011)
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문서

Knoevenagel Condensation is an organic reaction named after Emil Knoevenagel. It is a classic C-C bond formation reaction and a modification of the Aldol Condensation.

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