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Merck

HRH1

histamine receptor H1

동의어:
H1-R, hisH1
종:
UniProtKB ID:
Clone ID:
  • Human(3269) Summary: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless until recently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(15465) histamine receptor H1
  • Rat(24448) histamine receptor H 1
  • Zebrafish(735302) histamine receptor H1
  • dog(403813) histamine receptor H1
  • domestic cat(101088314) histamine receptor H1
  • cow(281231) histamine receptor H1
  • Horse(100034110) histamine receptor H1
  • chicken(100858928) histamine receptor H1
  • domestic guinea pig(100135539) histamine receptor H1
  • domestic guinea pig(100730517) histamine receptor H1
  • naked mole-rat(101715481) histamine receptor H1
  • sheep(101121717) histamine receptor H1

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Small Molecule - Agonist

Product Number
설명
Histamine, analytical standard,
human
Histamine, European Pharmacopoeia (EP) Reference Standard,
human
Histamine dihydrochloride, European Pharmacopoeia (EP) Reference Standard,
human
Histamine dihydrochloride, United States Pharmacopeia (USP) Reference Standard,
human
Histamine dihydrochloride, ≥99.0% (AT),
human

Small Molecule - Antagonist

Product Number
설명
Dexchlorpheniramine maleate, European Pharmacopoeia (EP) Reference Standard,
human
Clemastine fumarate, European Pharmacopoeia (EP) Reference Standard,
human
Doxylamine hydrogen succinate, European Pharmacopoeia (EP) Reference Standard,
human
Doxylamine for system suitability, European Pharmacopoeia (EP) Reference Standard,
human
Desloratadine, European Pharmacopoeia (EP) Reference Standard,
human

Antibodies

Product Number
설명
종별 반응성
응용분야
Monoclonal Anti-HRH1 antibody produced in mouse, clone 3D1, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
proximity ligation assay
Anti-Histamine Receptor 1 Antibody, CT, Chemicon®, from rabbit,
종별 반응성
bovine, mouse, rat
응용분야
ELISA
western blot

Small Molecule - Blocker

Product Number
설명
Cinnarizine, European Pharmacopoeia (EP) Reference Standard,
human
Cinnarizine, powder,
human
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
human
Orphenadrine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
human
Orphenadrine hydrochloride, ≥98.0% (AT),
human

Small Molecule - Inhibitor

Product Number
설명
Ketotifen fumarate salt, ,
human
L-Histidinol dihydrochloride, ≥98 (TLC),
mouse, rat, human
D-Histidine monohydrochloride monohydrate, ≥98% (TLC),
mouse, rat, human
Loratadine, ≥98% (HPLC), powder,
rat, human
Histamine, ≥97.0%,
human, rat

Small Molecule - Ligand

Product Number
설명
Loratadine, ≥98% (HPLC), powder,
rat, human
Cinnarizine, powder,
human

Small Molecule - Metabolite

Product Number
설명
1-Methylhistamine dihydrochloride, ≥98% (TLC), powder,
human

Small Molecule - Mixed Agonist/Antagonist

Product Number
설명
2-(2-Pyridyl)ethylamine, 95%,
human
Haloperidol, powder,
human, rat
Clozapine, ,
human, rat

esiRNA

Product Number
설명
MISSION® esiRNA, targeting human HRH1,
human
MISSION® esiRNA, targeting mouse Hrh1,
mouse