コンテンツへスキップ
Merck

The dorsal posterior insula subserves a fundamental role in human pain.

Nature neuroscience (2015-03-10)
Andrew R Segerdahl, Melvin Mezue, Thomas W Okell, John T Farrar, Irene Tracey
要旨

Several brain regions have been implicated in human painful experiences, but none have been proven to be specific to pain. We exploited arterial spin-labeling quantitative perfusion imaging and a newly developed procedure to identify a specific role for the dorsal posterior insula (dpIns) in pain. Tract tracing studies in animals identify a similar region as fundamental to nociception, which suggests the dpIns is its human homolog and, as such, a potential therapeutic target.

材料
製品番号
ブランド
製品内容

Sigma-Aldrich
カプサイシン, ≥95%, from Capsicum sp.
Sigma-Aldrich
カプサイシン, natural
USP
カプサイシン, United States Pharmacopeia (USP) Reference Standard
Sigma-Aldrich
カプサイシン, from Capsicum sp., ≥50% (HPLC)
Supelco
カプサイシン, analytical standard
Supelco
カプサイシン, Pharmaceutical Secondary Standard; Certified Reference Material
カプサイシン, European Pharmacopoeia (EP) Reference Standard