Potassium iodide catalyzed simultaneous C3-formylation and N-aminomethylation of indoles with 4-substituted-N,N-dimethylanilines.

Potassium iodide catalyzed simultaneous C3-formylation and N-aminomethylation of indoles with 4-substituted-N,N-dimethylanilines.

Organic & biomolecular chemistry (2012-11-13)

Lan-Tao Li, Hong-Ying Li, Li-Juan Xing, Li-Juan Wen, Peng Wang, Bin Wang

要旨

A one-pot dual functionalization of indoles has been developed. The simultaneous C3-formylation and N-aminomethylation of indoles can be achieved using readily available potassium iodide as a catalyst and tert-butyl peroxybenzoate as a co-oxidant.

材料

製品番号

ブランド

製品内容

221945

Sigma-Aldrich

ヨウ化カリウム, ACS reagent, ≥99.0%

207969

Sigma-Aldrich

ヨウ化カリウム, ReagentPlus^®, 99%

651818

Sigma-Aldrich

金エッチング剤、標準

204102

Sigma-Aldrich

ヨウ化カリウム, ≥99.99% trace metals basis

03124

Sigma-Aldrich

ヨウ化カリウム, puriss., meets analytical specification of Ph. Eur. BP, USP, 99.0-100.5% (calc. to the dried substance)

60399

Sigma-Aldrich

ヨウ化カリウム, BioUltra, ≥99.5% (AT)

236233

Sigma-Aldrich

N-メチルアニリン, ≥99%

M29304

Sigma-Aldrich

N-メチルアニリン, 98%

P8166

Sigma-Aldrich

ヨウ化カリウム, suitable for plant cell culture

24-4860

Sigma-Aldrich

ヨウ化カリウム, JIS special grade, ≥99.5%

24-4870

Sigma-Aldrich

ヨウ化カリウム, SAJ first grade, ≥99.5%

429422

Sigma-Aldrich

ヨウ化カリウム, AnhydroBeads^™, −10 mesh, 99.998% trace metals basis

60422

Sigma-Aldrich

ヨウ化カリウム, tested according to Ph. Eur.

P2963

Sigma-Aldrich

ヨウ化カリウム, BioXtra, ≥99.0%

24-4825

Sigma-Aldrich

ヨウ化カリウム溶液, 15 % (w/v)

209872

Sigma-Aldrich

4-tert-Butyl-N,N-dimethylaniline, 98%

49636

Supelco

N-メチルアニリン, analytical standard