V900422

葉酸

Vetec^™, reagent grade, ≥97%

• 別名: PteGlu, ビタミンM, プテロイル-L-グルタミン酸
• 実験式（ヒル表記法）: C₁₉H₁₉N₇O₆
• CAS番号: 59-30-3
• 分子量: 441.40
• Beilstein: 100781
• EC Number: 200-419-0
• MDL番号: MFCD00079305
• UNSPSCコード: 12352106
• PubChem Substance ID: 329829830

特性

• グレード: reagent grade
• 製品種目: Vetec^™
• アッセイ: ≥97%
• 形状: powder
• テクニック: HPLC: suitable
• 色: yellow to orange
• mp: >285 °C
• SMILES記法: NC(N1)=NC(C2=C1N=CC(CNC3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)=O
• InChI: 1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1
• InChI Key: OVBPIULPVIDEAO-LBPRGKRZSA-N

詳細

詳細

Folic acid belongs to vitamin B group and is also called as vitamin B₉ or folate. It is present as 5-methyltetrahydrofolate in humans. Grains, fruits and vegetables are dietary sources of folate. Pteroylmonoglutamate is a synthetic folate which comprises single glutamate and exists in the oxidized state.

生物化学的／生理学的作用

Folic acid is essential for cell growth, brain functioning and plays a key role on serine production from glycine. It also coordinates with vitamin B₁₂ in maintaining iron levels. Deficiency of folate is implicated in megaloblastic anemia. Folic acid aids in the repair and synthesis of DNA. Dietary supplementation and fortification of folate in foods is recommended for pregnant women especially in the first trimester to avoid congenital malformation and neural tube defects (NTDs). However, folate fortification may also impose a moderate risk of developing prostate cancer. Supplementation of folate to colon cancer cells diminishes iron levels and impairs the cell division.

法的情報

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1