おすすめの製品
製品種目
TOYOPEARL®
形状
slurry
特徴
counter ion Na+
包装
bottle of 250 mL
メーカー／製品名
Tosoh 22876
パラメーター
3 bar max. pressure
テクニック
LPLC: suitable
マトリックス
hydroxylated methacrylic polymer
マトリックス活性基
sulphonyl phase
粒径
35 μm
使用pH
3-13
キャパシティ
156 g/L±20 adsorption capacity (hIgG)
分離法
cation exchange
詳細
Toyopearl GigaCap S-650 resin is a high capacity, high resolution cation exchange resin* optimized for process scale applications, including the capture and purification of IgG as well as the polishing of monoclonal antibodies. A Toyopearl HW-65 polymeric bead has been chemically modified to provide a higher number of cationic binding sites for increased resin capacity.
While Toyopearl GigaCap S-650M resin was specifically optimized for IgG, with dynamic binding capacities in the vicinity of 140 mg/mL for IgG, it also exhibits high binding capacities for smaller proteins. Typical dynamic binding capacities for lysozyme are in excess of 160 mg/mL.
Toyopearl GigaCap S-650S resin has dynamic binding capacities approaching 165 g/L for gamma globulin. This high capacity, combined with the 35 μm mean particle size, makes Toyopearl GigaCap S-650S ideal for high resolution applications.
Toyopearl GigaCap S-650 resin is stable at high linear velocities, has good pressure-flow characteristics and will withstand back pressures up to 3 bar. The higher capacity and back pressure stability of Toyopearl GigaCap S-650 resin creates opportunities for increased throughput in downstream cation exchange purification steps.
Toyopearl GigaCap S-650M resin also has excellent base stability in 1.0 mol/L NaOH and shows robust clean in place (CIP) properties with minimal loss of capacity after 50 X 1 hour cycles of caustic exposure also using 1.0 mol/L NaOH. (data)
*specifically designed for packed bed use
While Toyopearl GigaCap S-650M resin was specifically optimized for IgG, with dynamic binding capacities in the vicinity of 140 mg/mL for IgG, it also exhibits high binding capacities for smaller proteins. Typical dynamic binding capacities for lysozyme are in excess of 160 mg/mL.
Toyopearl GigaCap S-650S resin has dynamic binding capacities approaching 165 g/L for gamma globulin. This high capacity, combined with the 35 μm mean particle size, makes Toyopearl GigaCap S-650S ideal for high resolution applications.
Toyopearl GigaCap S-650 resin is stable at high linear velocities, has good pressure-flow characteristics and will withstand back pressures up to 3 bar. The higher capacity and back pressure stability of Toyopearl GigaCap S-650 resin creates opportunities for increased throughput in downstream cation exchange purification steps.
Toyopearl GigaCap S-650M resin also has excellent base stability in 1.0 mol/L NaOH and shows robust clean in place (CIP) properties with minimal loss of capacity after 50 X 1 hour cycles of caustic exposure also using 1.0 mol/L NaOH. (data)
*specifically designed for packed bed use
規格
Clean in place with 0.5 M NaOH or 0.1 M HCl.
物理的形状
72% (v/v) slurry in 20% (v/v) ethanol
Shipped in 20% (v/v) ethanol.
法的情報
Toyopearl is a registered trademark of Tosoh Corporation
Toyopearl GigaCap is a registered trademark of Tosoh Corporation
シグナルワード
Warning
危険有害性情報
危険有害性の分類
Flam. Liq. 3
保管分類コード
3 - Flammable liquids
WGK
WGK 3
引火点(°F)
104.0 °F
引火点(℃)
40 °C
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
消防法
指定可燃物
可燃性液体類
労働安全衛生法名称等を表示すべき危険物及び有害物
名称等を表示すべき危険物及び有害物
労働安全衛生法名称等を通知すべき危険物及び有害物
名称等を通知すべき危険物及び有害物
最新バージョンのいずれかを選択してください：
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
製品に関するお問い合わせはこちら（テクニカルサービス）