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安全性情報

568533-U

Supelco

Discovery® HS C18 (5 µm) HPLC Columns

L × I.D. 25 cm × 10 mm, HPLC Column

別名:

Discovery RP18 HPLC Column

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About This Item

UNSPSCコード:
41115700
eCl@ss:
32110501
NACRES:
SB.52

product name

Discovery® HS C18 HPLCカラム, 5 μm particle size, L × I.D. 25 cm × 10 mm

物質

stainless steel column

品質水準

100

認証

suitable for USP L1

製品種目

Discovery®

特徴

endcapped

メーカー／製品名

Discovery®

包装

1 ea of

標識化の程度

20% Carbon loading

パラメーター

≤70 °C temp. range
400 bar pressure (5801 psi)

テクニック

HPLC: suitable

L × 内径

25 cm × 10 mm

表面積

300 m2/g

表面被覆率

3.2 μmol/m2

不純物

<10 ppm metals

マトリックス

silica gel, high purity, spherical particle platform
fully porous particle

マトリックス活性基

C18 (octadecyl) phase

粒径

5 μm

ポアサイズ

120 Å

operating pH range

2-8

アプリケーション

food and beverages

分離法

reversed phase

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詳細

Discovery® HS C18 HPLC column is specifically developed for pharmaceutical analyses and purification.

アプリケーション


  • Stereoselective separation of omeprazole and 5-hydroxy-omeprazole using dried plasma spots and a heart-cutting 2D-LC approach for accurate CYP2C19 phenotyping: This research utilizes the Discovery® HS C18 HPLC column for its superior selectivity and sensitivity in pharmacogenetic studies, providing vital data for personalized medicine approaches in drug metabolism (Abouir et al., 2024).

  • A stability indicating RP-HPLC method for determination of the COVID-19 drug molnupiravir applied using nanoformulations in permeability studies: This study highlights the effectiveness of the Discovery® HS C18 column in the rapid and accurate analysis of molnupiravir, emphasizing its role in supporting fast-paced pharmaceutical research and development (Reçber et al., 2022).

  • Sensitive Analysis of Idarubicin in Human Urine and Plasma by Liquid Chromatography with Fluorescence Detection: This application underlines the Discovery® HS C18 column′s high sensitivity and robustness in clinical diagnostics, crucial for monitoring therapeutic drugs and their metabolites in complex biological matrices (Maliszewska et al., 2020).

特徴および利点

  • 安定で、低ブリ-ドのLC-MS分離
  • 分析から分取まで適応可能
  • 安定性が高く、操作間、ロット間の再現性を保証
  • 疎水性が高く、難しい分析対象物の高い分離能

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法的情報

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany

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試験成績書（COA）

Lot/Batch Number
281713-01
281609-01
281606-01
281602-01
281353-01

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特定のバージョンが必要な場合は、ロット番号またはバッチ番号で特定の証明書を検索できます。

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以前この製品を購入いただいたことがある場合

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Abad Khan et al.
Talanta, 84(3), 789-801 (2011-04-13)
A new, simple, economical and validated high-performance liquid chromatography linked with electrochemical detector (HPLC-ECD) method has been developed and optimized for different experimental parameters to analyze the most common monothiols and disulfide (cystine, cysteine, homocysteine, methionine, reduced (GSH) and oxidized
Awantika Singh et al.
Rapid communications in mass spectrometry : RCM, 29(6), 485-496 (2015-07-15)
Adhatoda beddomei and Adhatoda vasica are popular Ayurvedic medicinal plants in India, belonging to the family Acanthaceae. Tricyclic quinazoline alkaloids are found to be the most abundant in these plants which are responsible for broad-spectrum medicinal properties. This study aims
Swati Jaiswal et al.
Journal of chromatographic science, 55(6), 617-624 (2017-03-24)
Tuberculosis (TB) with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome represents the most common infectious diseases worldwide. Anti-TB drugs are used concurrently with antiretroviral drug for treatment of TB-HIV co-morbidities. Due to lower risk of interaction with protease inhibitors, rifabutin is
Ismail Khan et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1033-1034, 261-270 (2016-09-07)
A simple, economical, fast, and sensitive RP-HPLC-UV method has been developed for the simultaneous quantification of Sorafenib and paclitaxel in biological samples and formulations using piroxicam as an internal standard. The experimental conditions were optimized and method was validated according
Lucie Zelena et al.
Journal of pharmaceutical and biomedical analysis, 137, 70-77 (2017-01-17)
Efavirenz is an antiretroviral drug used in the treatment of HIV-positive patients. A simple, fast and sensitive high-performance liquid chromatography (HPLC) method was developed in order to determine efavirenz in three types of samples provided from pharmacokinetic studies. The analysis
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プロトコル

GC Analysis of a Grain Fatty Acid Methyl Ester (FAME) Mix on SP™-2560

-11-eicosenoate; Methyl elaidate; Methyl linoleate; Methyl myristate; Methyl myristoleate; Methyl palmitate; Methyl palmitoleate; Methyl oleate; Methyl pentadecanoate; Methyl tridecanoate; Methyl behenate; Methyl caprylate; Methyl erucate; Methyl heptadecanoate; Methyl arachidate

GC Analysis of a Grain Fatty Acid Methyl Ester (FAME) Mix on SP™-2560

-11-eicosenoate; Methyl elaidate; Methyl linoleate; Methyl myristate; Methyl myristoleate; Methyl palmitate; Methyl palmitoleate; Methyl oleate; Methyl pentadecanoate; Methyl tridecanoate; Methyl behenate; Methyl caprylate; Methyl erucate; Methyl heptadecanoate; Methyl arachidate

関連コンテンツ

HPLC Discovery HS C18

HPLC DiscoveryBIO HS C18 products. Available in 3µm, 5µm and 10µm particle sizes.

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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