W3269

モノクロナール抗WDR62 マウス宿主抗体

~1.0 mg/mL, clone 3G8, purified immunoglobulin, buffered aqueous solution

• 別名: 抗C19orf14抗体, 抗WDリピートドメイン62抗体
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: mouse
• 結合体: unconjugated
• 抗体製品の状態: purified immunoglobulin
• 抗体製品タイプ: primary antibodies
• クローン: 3G8, monoclonal
• 形状: buffered aqueous solution
• 分子量: antigen ~170 kDa
• 化学種の反応性: human
• 濃度: ~1.0 mg/mL
• テクニック: indirect immunofluorescence: 0.5-1 μg/mL using HEK-293T cells over expressing human WDR62; western blot: 0.5-1 μg/mL using HEK-293T cells over expressing human WDR62
• アイソタイプ: IgG2a
• UniProtアクセッション番号: O43379
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... WDR62(284403)

詳細

詳細

Monoclonal Anti-WDR62 (mouse IgG2a isotype) is derived from the hybridoma 3G8 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a fusion protein encoding a fragment of human WDR62. WD repeat 62 is a member of WD-repeats and contains 15 WD repeats. WD-repeats consists of minimally conserved domains of 40-60 amino acids, which are initiated by glycine-histidine (GH) dipeptide 11 to 24 residues from the N-terminus and ends with tryptophan-aspartic acid (WD) dipeptide at the C terminus.

アプリケーション

Monoclonal Anti-WDR62 antibody produced in mouse has been used in immunoblotting and immunofluorescence.

生物化学的／生理学的作用

WD repeat 62 (WDR62) is identified in a phosphoproteome analysis as a protein associated with the mitotic spindle. It physically interacts with RNA-binding protein (RALY), TATA-binding protein (TBP), C1 or f103, mitogen-activated protein kinase (MAPK9) and itself. WDR62 potentiates c-Jun N-terminal kinase (JNK) activity. Mutations in this gene are linked to microcephaly and cortical malformations.

ターゲットの説明

WDR62 contains 15 WD repeats and has been identified in aphosphoproteome analysis as a protein associated with the mitotic spindle. WD40 proteins are implicated in many essential biologicalfunctions including adaptor/regulatory modules in signaltran

物理的形状

0.01M PBS溶液(pH 7.4, 15 mMアジ化ナトリウム含有)。

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable