T6402

抗τ (Tau) ウサギ宿主抗体

whole antiserum

• 別名: Anti-DDPAC, Anti-FTDP-17, Anti-MAPTL, Anti-MSTD, Anti-MTBT1, Anti-MTBT2, Anti-PPND, Anti-PPP1R103, Anti-TAU, Anti-tau-40
• MDL番号: MFCD00164745
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 結合体: unconjugated
• 抗体製品の状態: whole antiserum
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 含みます: 15 mM sodium azide
• 化学種の反応性: chicken, rat, mouse
• テクニック: western blot: 1:100 using rat or mouse brain tissue extract
• UniProtアクセッション番号: P19332
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... MAPT(4137)

詳細

詳細

Tau (τ), also known as MAPT (microtubule associated protein tau) is encoded by the gene mapped on human chromosome 17q21.3. It is highly expressed in neurons but is most prominent in axons.

Tau (τ), also known as microtubule associated protein tau (MAPT) is encoded by the gene mapped on human chromosome 17q21.3. It is highly expressed in neurons but is most prominent in axons. Tau is a heat stable microtubule associated protein (MAP) with a molecular weight of 55- 65 kDa.

特異性

幅広い種に反応性を示します。抗τ抗体は、MAP1, MAP2, チュ-ブリンとは反応しません。本抗体は、熱安定性微小管結合タンパク質(MAPs)の主要2クラスの内の1つであるτと結合します。

免疫原

ニワトリ胚脳微小管由来τタンパク質。

アプリケーション

Anti-τ (Tau) antibody produced in rabbit has been used as a primary antibody in western blotting.

生物化学的／生理学的作用

Removal of Tau (τ) results in developmental delay and learning disability. It participates in the pathology of Alzheimer′s disease (AD). Tau helps in the assembly and maintenance of microtubule structure.

Variation in the MAPT gene encoding tau protein results in frontotemporal dementia. Tau protein acts as a substrate for many kinases.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable