SML3556

Compound 18

≥98% (HPLC)

• 別名: MPO-IN-28, N-(7-Methoxy-4-methyl-2-quinazolinyl)guanidine
• 実験式（ヒル表記法）: C₁₁H₁₃N₅O
• CAS番号: 37836-90-1
• 分子量: 231.25
• UNSPSCコード: 51111800
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 色: white to beige
• 溶解性: DMSO: 2 mg/mL, clear (Warmed)
• 保管温度: -10 to -25°C
• SMILES記法: N(c1nc2c(c(n1)C)ccc(c2)OC)\C(=N\[H])\N
• InChI: 1S/C11H13N5O/c1-6-8-4-3-7(17-2)5-9(8)15-11(14-6)16-10(12)13/h3-5H,1-2H3,(H4,12,13,14,15,16)
• InChI Key: ZJBMSSBTCGJZEE-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

Agonist of Aedes aegypti mosquitoes NPY-like receptor 7 (NPYLR7) that inhibit mosquito attraction to humans; potent inhibitor of myeloperoxidase (MPO)

Compound 18 is an agonist of Aedes aegypti mosquitoes NPY-like receptor 7 (NPYLR7) that inhibit mosquito attraction to humans and other hosts. Compound 18 suppresses biting and blood-feeding on a live host. Also, It (MPO-IN-28) is a potent myeloperoxidase (MPO) inhibitor with an IC50 of 44 nM.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable