SML3409

ATN-224

≥95% (elemental analysis)

• 別名: 2-hydroxy-N,N,N-trimethylethanaminium tetrathiomolybdate, ALXN1840, Bis-Choline-Tetrathiomolybdate, Tiomolibdate Choline, WTX101
• 実験式（ヒル表記法）: C₁₀H₂₈N₂O₂ · MoS₄
• CAS番号: 649749-10-0
• 分子量: 432.54
• MDL番号: MFCD25976790
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥95% (elemental analysis)
• フォーム: powder
• 保管条件: desiccated
• 色: , Orange to very dark red
• 溶解性: H₂O: ≥0.1 mg/mL, clear
• 保管温度: -10 to -25°C
• SMILES記法: S=[Mo]([S-])([S-])=S.C[N+](C)(CCO)C.C[N+](C)(CCO)C
• InChI: 1S/2C5H14NO.Mo.4S/c2*1-6(2,3)4-5-7;;;;;/h2*7H,4-5H2,1-3H3;;;;;/q2*+1;;;;2*-1
• InChI Key: NEYVHGQOGHJAAD-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

ATN-224 (Bis-Choline-Tetrathiomolybdate) is an orally available and potent inhibitor of superoxide dismutase 1 (SOD1) that exhibit potent anticancer activities. ATN-224 is a copper chelator that rapidly lowers free coper levels and improve clinical symptoms in Wilson′s disease patients.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable