SML3391

Glatiramer acetate

≥95% (HPLC)

• 別名: Cop 1 (polyamide), Cop-1, Copaxone, Copolymer 1, GA, Polymer with L-alanine, L-lysine, L-tyrosine, and L-glutamic acid acetate
• 化学式: (C₉H₁₁NO₃)_a·(C₆H₁₄N₂O₂)_b ·(C₅H₉NO₄)_c ·(C₃H₇NO₂)_d ·x(CH₃CO₂H)
• UNSPSCコード: 12352200
• NACRES: NA.21

特性

• 品質水準: 100
• アッセイ: ≥95% (HPLC)
• フォーム: (Powder or Lyophilized powder or film)
• 保管条件: desiccated
• 色: white to beige
• 保管温度: -10 to -25°C
• SMILES記法: OC([C@@H](N)C)=O.OC(CC[C@H](N)C(O)=O)=O.NCCCC[C@H](N)C(O)=O.OC([C@@H](N)CC1=CC=C(C=C1)O)=O
• InChI: 1S/C9H11NO3.C6H14N2O2.C5H9NO4.C3H7NO2/c10-8(9(12)13)5-6-1-3-7(11)4-2-6;7-4-2-1-3-5(8)6(9)10;6-3(5(9)10)1-2-4(7)8;1-2(4)3(5)6/h1-4,8,11H,5,10H2,(H,12,13);5H,1-4,7-8H2,(H,9,10);3H,1-2,6H2,(H,7,8)(H,9,10);2H,4H2,1H3,(H,5,6)/t8-;5-;3-;2-/m0000/s1
• InChI Key: YLOCGHYTXIINAI-XKUOMLDTSA-N

詳細

生物化学的／生理学的作用

Glatiramer acetate, a myelin basic protein mimetic, is an immunomodulator used for treatment of Multiple Sclerosis. Glatiramer acetate is a mixture of synthetic peptides randomly composed of glutamic acid, lysine, alanine, and tyrosine. It reduces relapse rate and disease progression in Multiple Sclerosis. Its mechanism of action is not fully understood. Glatiramer acetate generates anti-inflammatory Th2 cells, which produce neurotrophic factors.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable