SML3099

Glyght

≥95% (HPLC)

• 別名: (E)-5-Phenyl-7-(pyridin-2-yldiazenyl)-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one
• 実験式（ヒル表記法）: C₂₀H₁₅N₅O
• CAS番号: 2505025-38-5
• 分子量: 341.37
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥95% (HPLC)
• フォーム: powder
• 保管条件: protect from light at room temperature
• 色: yellow to orange
• 溶解性: DMSO: 2 mg/mL, clear
• 保管温度: 2-8°C
• SMILES記法: O=C1NC(C=CC(/N=N/C2=NC=CC=C2)=C3)=C3C(C4=CC=CC=C4)=NC1
• InChI: 1S/C20H15N5O/c26-19-13-22-20(14-6-2-1-3-7-14)16-12-15(9-10-17(16)23-19)24-25-18-8-4-5-11-21-18/h1-12H,13H2,(H,23,26)/b25-24+
• InChI Key: MQMSSOZUTXPEIC-OCOZRVBESA-N

詳細

詳細

Glyght is a benzodiazepine-containing azobenzene compound that acts as a light-controlled negative allosteric modulator that is selective to glycine receptors. It is a powerful and effective compound that can operate in vivo. Glyght attaches to an allosteric site within the interface between the extracellular and transmembrane domains. It is an effective tool for researchers since it has broad activity in both homo- and heteromeric GlyRs across several species of fish and mammals. Moreover, Glyght is photo-switchable at 365 nm for trans-cis isomerization and 455 to 530 nm for cis-trans isomerization.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable