SML0574

YM-298198 hydrochloride

≥98% (HPLC)

• 別名: 6-Amino-N-cyclohexyl-N,3-dimethyl-thiazolo[3,2-a]benzimidazole-2-carboxamide hydrochloride
• 実験式（ヒル表記法）: C₁₈H₂₂N₄OS · HCl
• CAS番号: 1216398-09-2
• 分子量: 378.92
• MDL番号: MFCD08703122
• UNSPSCコード: 12352200
• PubChem Substance ID: 329825561
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• 形状: powder
• 保管条件: desiccated
• 色: white to beige
• 溶解性: H₂O: 5 mg/mL, clear
• 保管温度: 2-8°C
• SMILES記法: Cl.CN(C1CCCCC1)C(=O)c2sc3nc4ccc(N)cc4n3c2C
• InChI: 1S/C18H22N4OS.ClH/c1-11-16(17(23)21(2)13-6-4-3-5-7-13)24-18-20-14-9-8-12(19)10-15(14)22(11)18;/h8-10,13H,3-7,19H2,1-2H3;1H
• InChI Key: WYTJVUVCSUWZTH-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

YM-298198 is an orally active, noncompetitive mGlu1 receptor antagonist. The compound inhibits glutamate-induced inositol phosphate production in NIH3T3 cells (IC₅₀ = 16 nM). YM-298198 displays analgesic and antinociceptive properties in vivo.

特徴および利点

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable