SML0556

LY344864 hydrochloride

≥98% (HPLC)

• 別名: N-[(3R)-3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluoro-benzamide hydrochloride
• 実験式（ヒル表記法）: C₂₁H₂₂FN₃O · HCl
• CAS番号: 1217756-94-9
• 分子量: 387.88
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• 形状: powder
• 保管条件: desiccated
• 色: white to beige
• 溶解性: H₂O: 10 mg/mL, clear
• 保管温度: 2-8°C
• InChI: 1S/C21H22FN3O.ClH/c1-25(2)16-8-10-20-18(12-16)17-11-15(7-9-19(17)24-20)23-21(26)13-3-5-14(22)6-4-13;/h3-7,9,11,16,24H,8,10,12H2,1-2H3,(H,23,26);1H/t16-;/m1./s1
• InChI Key: OKUHLSYESBLBCP-PKLMIRHRSA-N

詳細

生物化学的／生理学的作用

LY344864 hydrochloride is a potent and selective 5-HT1F receptor agonist. It has an EC₅₀ of 3 nM, and displays > 80-fold selectivity over other 5-HT receptors

LY344864 might be useful in the treatment approach for migraine. LY344864 is found to prevent the extravasation of dura protein and reduce c-fos like immunoreactions induced by capsaicin.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable