SML0507

NPC26

≥98% (HPLC)

• 別名: 4,5,6,7-Tetrahydro-5,5,7,7-tetramethyl-2-[[(5-nitro-2-thienyl)carbonyl]amino]-thieno[2,3-c]pyridine-3-carboxylic acid ethyl ester, NPC-26
• 実験式（ヒル表記法）: C₁₉H₂₃N₃O₅S₂
• CAS番号: 864860-32-2
• 分子量: 437.53
• MDL番号: MFCD04428321
• UNSPSCコード: 12352200
• PubChem Substance ID: 329825516
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 色: light orange to dark orange
• 溶解性: DMSO: 2 mg/mL, clear (warmed)
• 保管温度: 2-8°C
• SMILES記法: CCOC(=O)c1c2CC(C)(C)NC(C)(C)c2sc1NC(=O)c3ccc(s3)[N+]([O-])=O
• InChI: 1S/C19H23N3O5S2/c1-6-27-17(24)13-10-9-18(2,3)21-19(4,5)14(10)29-16(13)20-15(23)11-7-8-12(28-11)22(25)26/h7-8,21H,6,9H2,1-5H3,(H,20,23)
• InChI Key: DWGSXNATVAGHKZ-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

NPC26 induces mitochondrial fragmentation and cell death in RAS expressing cells, similar to erastin. The effects of NPC26 are independent of ROS scavengers, which can block cell death induced by erastin.

NPC26 induces mitochondrial fragmentation and cell death in RAS expressing cells.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable