SML0356

Etonogestrel

≥98% (HPLC)

• 別名: (17α)-13-Ethyl-17-hydroxy-11-methylene-18,19-dinorpregn-4-en-20-yn-3-one, 3-Keto-desogestrel, 3-Oxo-desogestrel
• 実験式（ヒル表記法）: C₂₂H₂₈O₂
• CAS番号: 54048-10-1
• 分子量: 324.46
• EC Number: 258-936-2
• MDL番号: MFCD00867863
• UNSPSCコード: 51111800
• PubChem Substance ID: 329825358
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 光学活性: [α]/D +80 to +95°, c = 1 (CHCl3)
• 色: white to beige
• 溶解性: DMSO: >5 mg/mL
• 保管温度: −20°C
• SMILES記法: CC[C@]12CC(=C)[C@H]3[C@@H](CCC4=CC(=O)CC[C@H]34)[C@@H]1CC[C@@]2(O)C#C
• InChI: 1S/C22H28O2/c1-4-21-13-14(3)20-17-9-7-16(23)12-15(17)6-8-18(20)19(21)10-11-22(21,24)5-2/h2,12,17-20,24H,3-4,6-11,13H2,1H3/t17-,18-,19-,20+,21-,22-/m0/s1
• InChI Key: GCKFUYQCUCGESZ-BPIQYHPVSA-N
• 遺伝子情報: human ... PGR(5241)

詳細

生物化学的／生理学的作用

Etonogestrel is a lipophilic molecule. Pharmacokinetics studies reveal that etonogestrel is bound to protein albumin in the blood. This remains independent of both endogenous and exogenous concentration of estradiol.

Etonogestrel is a progestin, contraceptive.

Etonogestrel is a third-generation progestin contraceptive. Etonogestrel is used as a contraceptive itself and is also the active metabolite of the drug desogestrel used in some combination contraceptives.

特徴および利点

This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全性情報

• ピクトグラム: GHS08
• シグナルワード: Danger
• 危険有害性情報: H351,H360
• 注意書き: P201 - P308 + P313
• 危険有害性の分類: Carc. 2 - Repr. 1B
• 保管分類コード: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable