SML0340

Hydroxy-Dynasore

≥98% (HPLC)

• 別名: 3-Hydroxy-2-naphthalenecarboxylic acid 2-[(2,4,5-trihydroxyphenyl)methylene]hydrazide, 3-Hydroxy-N′-[(2,4,5-trihydroxyphenyl)methylidene]naphthalene-2-carbohydrazide
• 実験式（ヒル表記法）: C₁₈H₁₄N₂O₅
• CAS番号: 1256493-34-1
• 分子量: 338.31
• MDL番号: MFCD23704787
• UNSPSCコード: 12352200
• PubChem Substance ID: 329825345
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 保管条件: protect from light
• 色: faintly yellow to dark yellow
• 溶解性: DMSO: >10 mg/mL
• 保管温度: 2-8°C
• SMILES記法: Oc1cc(O)c(\C=N\NC(=O)c2cc3ccccc3cc2O)cc1O
• InChI: 1S/C18H14N2O5/c21-14-8-17(24)16(23)7-12(14)9-19-20-18(25)13-5-10-3-1-2-4-11(10)6-15(13)22/h1-9,21-24H,(H,20,25)/b19-9+
• InChI Key: UAXHPUSKEWEOAP-DJKKODMXSA-N

詳細

生物化学的／生理学的作用

Hydroxy-Dynasore is a cell permeable and potent dynamin inhibitor that prevents uptake of recombinant botulinum neurotoxin A heavy chain binding domain (BoNT/A-Hc). Apparently, Hydroxy-Dynasore prevents dynamin-mediated fission of endocytic vesicles from the plasma membrane.

Hydroxy-Dynasore is a cell permeable and potent dynamin inhibitor.

その他情報

Air sensitive.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable