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製品名
カスパーゼ9基質、発色基質, ≥95% (HPLC)
アッセイ
≥95% (HPLC)
フォーム
lyophilized
組成
Peptide Content, ≥75%
保管条件
protect from light
保管温度
−20°C
関連するカテゴリー
Amino Acid Sequence
Ac-Leu-Glu-His-Asp-pNA
アプリケーション
Caspase 9 is an initiator caspase that cleaves procaspase 3 and procaspase 7 to propagate the apoptotic cascade. Caspase 9 may be detected using a variety of chromogenic and fluorogenic peptide substrates built around the LEHD peptide core such as the chromogenic substrate Ac-LEHD-pNa (Ac-Leu-Glu-His-Asp-p-nitroanalide).
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
最新バージョンのいずれかを選択してください：
Yinyuan Wu et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 27(5), 539-546 (2011-06-22)
Oxidative stress is known to be involved in a variety of pathological processes including atherosclerosis, diabetes, and neurodegenerative diseases. Understanding how intracellular signaling pathways respond to oxidative stress will have a significant implication in the therapy of these diseases. In
Lin-Li Zhou et al.
European journal of pharmacology, 670(2-3), 399-408 (2011-09-29)
Psoriasis is a chronic inflammatory skin disease affecting 1-3% of the world's population. Traditional Chinese medicines have been extensively used for treating psoriasis with promising clinical results. Celastrol, a triterpenoid isolated from a Chinese herb Celastrus orbiculatus caulis, has been
Juan Liu et al.
Molecular cancer, 10, 95-95 (2011-08-02)
Caspase-8 is a key upstream mediator in death receptor-mediated apoptosis and also participates in mitochondria-mediated apoptosis via cleavage of proapoptotic Bid. However, the role of caspase-8 in p53- and p73-dependent apoptosis induced by genotoxic drugs remains unclear. We recently reported
Aza-derivatives of resveratrol are potent macrophage migration inhibitory factor inhibitors.
Fujita, Y., et al.
Investigational New Drugs (2011)
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