おすすめの製品
アッセイ
≥95% (HPLC)
形状
lyophilized
組成
Peptide Content, ≥80%
保管条件
protect from light
保管温度
−20°C
Amino Acid Sequence
Ac-Val-Asp-Val-Ala-Asp-al
アプリケーション
Caspase 2 Inhibitor (Ac-VDVAD-CHO) is a non-selective (also inhibits caspase 3) but powerful inhibitor of caspase 2 used to study the role of caspase 2 in cell processes.
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Michel C Maillard et al.
Bioorganic & medicinal chemistry, 19(19), 5833-5851 (2011-09-10)
Several caspases have been implicated in the pathogenesis of Huntington's disease (HD); however, existing caspase inhibitors lack the selectivity required to investigate the specific involvement of individual caspases in the neuronal cell death associated with HD. In order to explore
Bin Fang et al.
Journal of molecular biology, 360(3), 654-666 (2006-06-20)
The molecular basis for the substrate specificity of human caspase-3 has been investigated using peptide analog inhibitors and substrates that vary at the P2, P3, and P5 positions. Crystal structures were determined of caspase-3 complexes with the substrate analogs at
Ju Youn Kim et al.
Cell, 175(1), 133-145 (2018-09-18)
Nonalcoholic fatty liver disease (NAFLD) progresses to nonalcoholic steatohepatitis (NASH) in response to elevated endoplasmic reticulum (ER) stress. Whereas the onset of simple steatosis requires elevated de novo lipogenesis, progression to NASH is triggered by accumulation of hepatocyte-free cholesterol. We
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