SAB5702978

Anti-FMRP Antibody, clone 4Y8I5, Rabbit Monoclonal

• 別名: FMRP, FRAXA, POF, POF1
• UNSPSCコード: 12352203
• NACRES: NA.46

特性

• 由来生物: rabbit
• 品質水準: 100
• 物質: colorless
• クローン: 4Y8I5, monoclonal
• 形状: liquid
• 分子量: 70-80 kDa
• 化学種の反応性: human, rat, rat
• 濃度: 0.5 mg/mL
• テクニック: immunohistochemistry: 1:50 - 1:200; immunoprecipitation (IP): 1:50 - 1:200; western blot: 1:500 - 1:2000
• 色: colorless
• アイソタイプ: IgG
• 免疫原配列: MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDINESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACD
• UniProtアクセッション番号: Q06787
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... FMR1(2332)

詳細

詳細

The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010]

免疫原

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human FMRP (Q06787).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

アプリケーション

WB, IHC, IP

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1