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由来生物
rabbit
品質水準
物質
colorless
クローン
2V1Z6, monoclonal
形状
liquid
分子量
110 kDa
化学種の反応性
human, rat, rat
濃度
0.5 mg/mL
テクニック
immunohistochemistry: 1:50 - 1:200
western blot: 1:500 - 1:2000
色
colorless
アイソタイプ
IgG
免疫原配列
MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNAS
UniProtアクセッション番号
輸送温度
wet ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... FGFR3(2261)
詳細
This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. Three alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Jul 2009]
免疫原
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human FGFR3 (P22607).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
アプリケーション
WB, IHC
保管分類コード
10 - Combustible liquids
WGK
WGK 1
試験成績書(COA)
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